Science. 1967 Feb 24;155(3765):1026-7. doi: 10.1126/science.155.3765.1026.
A number of crystalline compounds isolated from peel of tangerines resistant to "mal secco" were characterized and tested for fungistatic activity toward Deuterophoma tracheiphila. Nobiletin exhibited strong fungistatic activity, tangeritin was weakly active, and hesperidin slightly stimulated fungal growth. Rough lemon seedlings, inoculated with the pathogenic fungus, rapidly developed the symptoms of mal secco, whereas continuous infusion of the inoculated seedlings with nobiletin solution largely prevented appearance of the disease.
从抗“枯水病”的蜜柑果皮中分离出的几种结晶性化合物的特性及其对梨孢Deuterophoma tracheiphila 的抑菌活性进行了测试。诺必灵具有很强的抑菌活性，桔皮苷活性较弱，橙皮苷略有刺激真菌生长的作用。用病原菌接种的粗柠檬实生苗迅速出现枯水病症状，而连续向接种实生苗输注诺必灵溶液则在很大程度上防止了疾病的发生。
