Spagnolo A, Morisi G, Marano G, Righetti G, Maietta A, Menotti A
Laboratory of Epidemiology and Biostatistics, Istituto Superiore di Sanità, Rome, Italy.
Eur J Epidemiol. 1991 Nov;7(6):654-7. doi: 10.1007/BF00218677.
The aim of this study was to determine, in a population of Italian adolescents, the association of serum selenium levels with precursors of biochemical and anthropometric variables known as being among the major risk factors for cardiovascular diseases in the adult population. The following measurements were taken in a school sample of 627 adolescents (aged 12-13 years); serum selenium, total cholesterol, high density lipoprotein cholesterol, non-HDL cholesterol, height, weight, body mass index, systolic blood pressure and diastolic blood pressure. The serum selenium levels were slightly higher in males (83.1 +/- 10.1 micrograms/l) than in females (81.7 +/- 11.0 micrograms/l), but the difference was not statistically significant. Serum selenium was positively correlated with total cholesterol, diastolic blood pressure and HDL cholesterol in both sexes; moreover it was positively correlated with non-HDL cholesterol and negatively correlated with height in males only.
本研究的目的是在一群意大利青少年中,确定血清硒水平与生化和人体测量变量的前驱因素之间的关联,这些变量被认为是成年人群心血管疾病的主要危险因素。在一个由627名青少年(年龄在12至13岁之间)组成的学校样本中进行了以下测量:血清硒、总胆固醇、高密度脂蛋白胆固醇、非高密度脂蛋白胆固醇、身高、体重、体重指数、收缩压和舒张压。男性的血清硒水平(83.1±10.1微克/升)略高于女性(81.7±11.0微克/升),但差异无统计学意义。血清硒与男女的总胆固醇、舒张压和高密度脂蛋白胆固醇呈正相关;此外,仅在男性中,血清硒与非高密度脂蛋白胆固醇呈正相关,与身高呈负相关。