Bueno Cavanillas A, Rodrìguez-Contreras R, Delgado Rodriguez M, Moreno Abril O, López Gigosos R, Guillen Solvas J, Gálvez Vargas R
Department of Preventive Medicine and Public Health, University Hospital of Granada, Spain.
Eur J Epidemiol. 1991 Nov;7(6):670-6. doi: 10.1007/BF00218680.
To evaluate the relationship between duration of preoperative stay and the risk of nosocomial infection, we studied 449 patients who underwent surgery at the University Hospital of Granada during the first six months of 1986. Patients were chosen from two cross-sectional surveys. Nosocomial infection was studied throughout each patient's hospital stay. Other variables included preoperative stay, age, severity and total length of stay. The data were analyzed by comparing nosocomial infection for different lengths of preoperative hospitalization, age and severity by calculating the Odds Ratio. The effects of age and severity were studied by stratifying patients by duration of preoperative stay. Two multivariate regression models were used to confirm the results of the stratified analysis. The results suggest that lengthening the preoperative stay may increase the risk of nosocomial infection in surgical wounds and in other sites, and may simultaneously potentiate the effects of other risk factors such as age and severity of the patient's condition, whose influence on susceptibility to infection increases with the duration of preoperative stay.
为评估术前住院时间与医院感染风险之间的关系，我们研究了1986年上半年在格拉纳达大学医院接受手术的449例患者。患者选自两项横断面调查。在每位患者的整个住院期间对医院感染进行研究。其他变量包括术前住院时间、年龄、病情严重程度和总住院时间。通过计算比值比，比较不同术前住院时间、年龄和病情严重程度的医院感染情况，对数据进行分析。通过按术前住院时间对患者进行分层，研究年龄和病情严重程度的影响。使用两个多变量回归模型来证实分层分析的结果。结果表明，延长术前住院时间可能会增加手术伤口及其他部位医院感染的风险，并且可能同时增强其他风险因素的影响，如患者年龄和病情严重程度，其对感染易感性的影响会随着术前住院时间的延长而增加。
