Tocalli L, Nardi G, Mammino A, Salvaggio A, Salvaggio L
Laboratory of Clinical Chemistry and Microbiology, L. Sacco Hospital, Milan, Italy.
Eur J Epidemiol. 1991 Nov;7(6):690-5. doi: 10.1007/BF00218684.
We reviewed the cases of typhoid fever (3 cases) and non-typhoid salmonellosis (62 cases) diagnosed from 1987 to 1989 in the Laboratory of Clinical Chemistry and Microbiology of the 'L.Sacco' Hospital, Milan. Two cases of typhoid fever and 24 cases of non-typhoid salmonellosis occurred in patients without clinical symptoms of HIV infection. One case of typhoid fever and 38 cases of non-typhoid salmonellosis occurred in patients with clinical symptoms of HIV infection. In AIDS patients living in the Milan province the annual incidence of non-typhoid salmonellosis was estimated to be 100-fold greater than that observed in the general population. In patients with non-typhoid salmonellosis, bacteremias was found only in subjects with HIV disease (P = 0.0009). The frequency of bacteremia was higher in patients with AIDS than in patients with other manifestations of HIV disease (P = 0.0356). Finally, a significant difference between patients with and without HIV disease was found with regard to Salmonella serotypes distribution (P = 0.0196).
我们回顾了1987年至1989年在米兰“L.Sacco”医院临床化学与微生物学实验室诊断的伤寒热（3例）和非伤寒沙门氏菌病（62例）病例。2例伤寒热和24例非伤寒沙门氏菌病发生在无HIV感染临床症状的患者中。1例伤寒热和38例非伤寒沙门氏菌病发生在有HIV感染临床症状的患者中。据估计，居住在米兰省的艾滋病患者中非伤寒沙门氏菌病的年发病率比普通人群中观察到的发病率高100倍。在非伤寒沙门氏菌病患者中，仅在患有HIV疾病的受试者中发现菌血症（P = 0.0009）。艾滋病患者中菌血症的发生率高于患有其他HIV疾病表现的患者（P = 0.0356）。最后，在有和没有HIV疾病的患者之间，沙门氏菌血清型分布存在显著差异（P = 0.0196）。
