巴勒莫地区乙型肝炎的流行病学特征：乙肝病毒传播的变化

Epidemiological aspects of hepatitis B in Palermo: changes in HBV spread.

作者信息

Intonazzo V, La Rosa G, Massenti M F, Perna A M, Restivo E, Sferlazzo A, Dardanoni L

机构信息

Dipartimento di Igiene e Microbiologia, G. D'Alessandro dell'Università, Palermo, Italy.

出版信息

Eur J Epidemiol. 1991 Nov;7(6):696-8. doi: 10.1007/BF00218685.

DOI:10.1007/BF00218685

PMID:1783065

Abstract

Prevalence of HBV infection in Palermo was investigated in 1989, in comparison with similar data observed in 1982. Between September 1988 and April 1989, 1001 serum samples taken from healthy individuals or from patients with pathology unrelated to liver diseases, in the age groups 0 to 59 years, were collected. Prevalence of HBsAg and anti-HBc was, respectively, 2.7% and 24.3% in males, 2.3% and 19% in females. Prevalence was inversely related to socioeconomic level as defined by occupation, educational level and area of residence. Prevalence of HBV markers in 1989 was compared with that of a sample of sera taken in 1982 and stored at -20 degrees C. Prevalence was lower in 1989 for age groups under 20, while no difference was seen in older age groups.

摘要

1989年对巴勒莫地区乙肝病毒（HBV）感染的流行情况进行了调查，并与1982年观察到的类似数据进行了比较。在1988年9月至1989年4月期间，收集了1001份来自0至59岁健康个体或患有与肝脏疾病无关的疾病患者的血清样本。男性中乙肝表面抗原（HBsAg）和乙肝核心抗体（抗-HBc）的流行率分别为2.7%和24.3%，女性中分别为2.3%和19%。流行率与根据职业、教育水平和居住地区定义的社会经济水平呈负相关。将1989年乙肝病毒标志物的流行率与1982年采集并储存在-20摄氏度的血清样本的流行率进行了比较。1989年20岁以下年龄组的流行率较低，而在年龄较大的组中未观察到差异。