Nelson T J
Neural Systems Section, National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, MD 20892.
J Chromatogr. 1991 Dec 20;587(2):129-36. doi: 10.1016/0021-9673(91)85149-a.
A method is described for deconvoluting chromatograms which contain overlapping peaks. Parameters can be selected to ensure that attenuation of peak areas is uniform over any desired range of peak widths. A simple extension of the method greatly reduces the negative overshoot frequently encountered with deconvolutions. The deconvoluted chromatograms are suitable for integration by conventional methods.
