鲤鱼萝藦抗生育成分的研究。

Studies on the antifertility components from Marsdenia koi.

作者信息

Yuan J L, Ding W P, Shi J P, Lu Z Z, Zhou B N, Erdelmeier C A, Cordell G A, Fong H H, Farnsworth N R

机构信息

Family Planning Research Institute, Tongji Medical University, Wuhan.

出版信息

J Tongji Med Univ. 1991;11(3):165-8. doi: 10.1007/BF02888129.

DOI:10.1007/BF02888129

PMID:1784046

Abstract

By random screening test, Marsdenia koi was found to have antifertility activity on SD rat. From MeOH extracts of this plant two steroidal glycosides, marsdekoiside A and B, were isolated, and their structures were elucidated on the basis of spectral evidence and by comparison of the hydrolysis products with the authentic samples. Both are newly identified compounds, and marsdekoiside A has good antifertility activity.

摘要

通过随机筛选试验，发现鲤鱼吊灯花对SD大鼠具有抗生育活性。从该植物的甲醇提取物中分离出两种甾体糖苷，即鲤鱼吊灯花苷A和B，并根据光谱数据以及将水解产物与标准样品进行比较来阐明它们的结构。两者均为新鉴定的化合物，且鲤鱼吊灯花苷A具有良好的抗生育活性。