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血脑屏障:血液与脑细胞外液之间主动阳离子转运的证据。

Blood-Brain Barrier: Evidence for Active Cation Transport between Blood and the Extraceliular Fluid of Brain.

作者信息

Bito L Z

出版信息

Science. 1969 Jul 4;165(3888):81-3. doi: 10.1126/science.165.3888.81.

DOI:10.1126/science.165.3888.81
PMID:17840696
Abstract

The concentration gradients of Mg(++) and K(+) in the cerebrospinal fluid system indicate that the (Mg(++)) is higher and the (K(+)) is lower in the extra-cellular fluid of the cerebral cortex than the concentrations of these cations in either plasma-dialysate or cisternal fluid. Such cation distribution demonstrates the existence of an active transport process across the blood-brain barrier.

摘要

脑脊液系统中镁离子(Mg(++))和钾离子(K(+))的浓度梯度表明,大脑皮质细胞外液中镁离子(Mg(++))浓度高于血浆透析液或脑池液中这些阳离子的浓度,而钾离子(K(+))浓度则低于血浆透析液或脑池液中这些阳离子的浓度。这种阳离子分布表明存在一种跨越血脑屏障的主动转运过程。

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Potassium transfer from brain to blood during sustained hyponatraemia in the newborn calf.新生小牛持续性低钠血症期间钾从脑到血的转移
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[Studies on the area postrema of Gallus domesticus. II. The morphological problem of the existence of a blood-brain barrier].[家鸡最后区的研究。II. 血脑屏障存在的形态学问题]
Acta Neuropathol. 1972;21(4):308-15. doi: 10.1007/BF00685138.