Tani M, Bossini S, Maffetti G
Laboratorio Analisi Chimico-Cliniche e Microbiologia, Ospedale Civile, Gavardo, Brescia.
Minerva Ginecol. 1991 Nov;43(11):519-24.
During a 3 month period the Authors have evaluated the possible modification of some coagulation parameters which can be of relevance for thrombophilic state. Fibrinogen and factor VII were measured and following 3 months of oestro-progestinic treatment in 11 women in good general health and without known controindications to contraceptive treatment. No significant difference in some levels of fibrinogen and factor VII were found. We conclude that in the short term fibrinogen and factor VII are not significantly altered but a longer period of follow up is indicated in order to estimate the risk of cardiovascular accidents.
在3个月的时间里，作者评估了一些可能与血栓形成倾向相关的凝血参数的变化。对11名身体健康且无已知避孕治疗禁忌证的女性进行了雌激素 - 孕激素治疗3个月后，测量了纤维蛋白原和凝血因子VII。未发现纤维蛋白原和凝血因子VII的某些水平有显著差异。我们得出结论，短期内纤维蛋白原和凝血因子VII没有显著改变，但为了评估心血管意外的风险，需要进行更长时间的随访。
