Vianna Gustavo José Caldas, de Melo Alan Lane
Laboratório de Taxonomia e Biologia de Invertebrados, Departamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
J Helminthol. 2007 Dec;81(4):345-9. doi: 10.1017/S0022149X07818566. Epub 2007 Sep 11.
A mouse-derived strain of Rodentolepis ( = Hymenolepis) nana was transferred to the Mongolian jird Meriones unguiculatus. It was found that M. unguiculatus has low susceptibility to R. nana mouse isolates. Likewise, adaptation of the parasite to jird hosts, in the absence of dexamethasone treatment, was not demonstrable, at least during ten-passage trials. Nevertheless, the parasite was able to establish, grow and develop to gravid adults in M. unguiculatus treated daily with dexamethasone. Prepatent periods in dexamethasone-treated jirds in ten-passage series ranged from 10 to 17 days post-infection (DPI), the average being 12 days, and the patent periods lasted from 18 to 30 DPI, with an average of 25 days. The population pattern of faecal egg output in immunosuppressed jirds suggests that under a daily dexamethasone treatment protocol, the parasite is able to maintain egg production as long as treatment is sustained.
一种源自小鼠的微小膜壳绦虫（=缩小膜壳绦虫）菌株被转移到长爪沙鼠（Meriones unguiculatus）体内。结果发现，长爪沙鼠对微小膜壳绦虫的小鼠分离株敏感性较低。同样，在没有地塞米松治疗的情况下，至少在十代试验期间，未证实该寄生虫能适应沙鼠宿主。然而，在用地塞米松每日治疗的长爪沙鼠中，该寄生虫能够建立感染、生长并发育为成熟成虫。在十代系列试验中，用地塞米松治疗的沙鼠的潜伏期为感染后10至17天（DPI），平均为12天，排虫期持续18至30 DPI，平均为25天。免疫抑制沙鼠粪便虫卵排出量的种群模式表明，在每日地塞米松治疗方案下，只要持续治疗，该寄生虫就能维持产卵。
