Feldmeier H G, Rahn H W, Wolf I
Berlin-Chemie, Abteilung für galenische Forschung.
Pharmazie. 1991 Jul;46(7):517-9.
A method is described for the quantitative determination of amorphous and crystalline insulin contents in insulin zinc suspensions. The different resolving rates of the modifications in acid dilutions are utilized for the test. Measurements are made by UV spectroscopy. Information is given on the application of this method for the analysis of the course of insulin crystallization and it is compared with the USP XXI method.
本文描述了一种定量测定胰岛素锌混悬液中非晶态和结晶态胰岛素含量的方法。该测试利用了不同形态胰岛素在酸性稀释液中的不同溶解速率。通过紫外光谱法进行测量。文中给出了该方法在分析胰岛素结晶过程中的应用信息，并与美国药典第二十一版方法进行了比较。
