Kondo H, Ishikawa M, Maeda H, Onuma M, Masuda M, Shibuya H, Koie H, Sato T
Laboratory of Veterinary Pathology, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa, Japan.
Vet Pathol. 2007 Sep;44(5):691-4. doi: 10.1354/vp.44-5-691.
A 6-year-old male cross-breed rabbit ( Oryctolagus cuniculus) was presented with lameness and severe swelling from the right shoulder to brachium. On 16-detector helical computed tomography images of the amputated right forelimb after being fixed in formalin, evident proliferative and destructive lesions of bone were observed. On histologic examination, the tumor was composed of proliferating neoplastic cells that resembled histiocytes, with abundant osteoid production. A large number of multinucleated giant cells were found throughout. This case was diagnosed as osteosarcoma by clinical, radiographic, and histologic findings. This is a rare case report of osteosarcoma in a rabbit consistent with canine predilection sites.
一只6岁的雄性杂种兔（穴兔）出现跛行，右肩部至臂部严重肿胀。在福尔马林固定后的右前肢截肢的16排螺旋计算机断层扫描图像上，观察到明显的骨增殖性和破坏性病变。组织学检查显示，肿瘤由增殖的类似组织细胞的肿瘤细胞组成，有大量类骨质生成。可见大量多核巨细胞。根据临床、影像学和组织学检查结果，该病例被诊断为骨肉瘤。这是一例罕见的兔骨肉瘤病例报告，其发病部位与犬好发部位一致。
