一种从欧洲山杨茎瘤中提取的新型抗氧化剂苯基二糖。
A novel antioxidant phenyl disaccharide from Populus tremula knotwood.
作者信息
Neacsu Madalina, Micol Vicente, Pérez-Fons Laura, Willför Stefan, Holmbom Bjarne, Mallavia Ricardo
机构信息
Department of Chemistry and Biochemistry, University of Agricultural Sciences and Veterinary Medicine, Manastur 3-5, 400372 Cluj, Napoca, Romania.
出版信息
Molecules. 2007 Feb 19;12(2):205-17. doi: 10.3390/12020205.
The complete characterization of two compounds obtained from the acetone extract of Populus tremula knotwood has been was achieved using LC-DAD-MS, MS/MS, IR and NMR. The new compounds were unequivocally identified as a mixture of the ester isomers of the (E) and (Z) p-coumarate of 1-O-rutinose. The isomers showed the capacity to inhibit lipid peroxidation induced by tert-butylhydroperoxide and to trap peroxyl radicals, as determined by a chemiluminescence method. These new phenyl disaccharides also showed a significant ORAC (oxygen radical absorbance capacity) value, i.e. 11.7 microM TE (Trolox Equivalents).
利用液相色谱 - 二极管阵列 - 质谱联用仪（LC - DAD - MS）、串联质谱（MS/MS）、红外光谱（IR）和核磁共振（NMR）对从欧洲山杨节木丙酮提取物中获得的两种化合物进行了完整表征。新化合物被明确鉴定为1 - O - 芸香糖的（E）和（Z）对香豆酸酯异构体的混合物。通过化学发光法测定，这些异构体显示出抑制叔丁基过氧化氢诱导的脂质过氧化和捕获过氧自由基的能力。这些新的苯基二糖还显示出显著的氧自由基吸收能力（ORAC）值，即11.7微摩尔TE（Trolox当量）。
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