Aguirre-Balsalobre F, González-Herrera M, Mengual-Verdú E, García-Conca V, Hueso-Abancens J R
Hospital Universitario San Juan de Alicante, Alicante, Spain.
Arch Soc Esp Oftalmol. 2007 Sep;82(9):583-6. doi: 10.4321/s0365-66912007000900015.
Botulism is currently an uncommon disease in which the botulinum toxin causes a progressive muscular paralysis that can lead to the death due to a failure of respiratory muscles.
Two brothers, both addicted to cocaine, came to the casualty department because of a decrease of near visual acuity and bilateral mydriasis. Two days later, they developed eyelid ptosis, asymmetric dysfunction of the extraocular muscles and vomiting.
The presence of a paralysis of accommodation, with bilateral mydriasis that reacts to pilocarpine, makes it necessary to consider botulism as a possible cause.
肉毒中毒目前是一种罕见疾病,肉毒杆菌毒素会导致进行性肌肉麻痹,可因呼吸肌衰竭而致死。
两名兄弟均沉迷于可卡因,因近视力下降和双侧瞳孔散大前往急诊科。两天后,他们出现眼睑下垂、眼球外肌不对称功能障碍及呕吐症状。
存在调节麻痹,伴有对毛果芸香碱有反应的双侧瞳孔散大,这使得有必要将肉毒中毒视为可能的病因。