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[两名可卡因成瘾兄弟同时患肉毒中毒]

[Simultaneous botulism in two brothers addicted to cocaine].

作者信息

Aguirre-Balsalobre F, González-Herrera M, Mengual-Verdú E, García-Conca V, Hueso-Abancens J R

机构信息

Hospital Universitario San Juan de Alicante, Alicante, Spain.

出版信息

Arch Soc Esp Oftalmol. 2007 Sep;82(9):583-6. doi: 10.4321/s0365-66912007000900015.

Abstract

INTRODUCTION

Botulism is currently an uncommon disease in which the botulinum toxin causes a progressive muscular paralysis that can lead to the death due to a failure of respiratory muscles.

CLINICAL CASE

Two brothers, both addicted to cocaine, came to the casualty department because of a decrease of near visual acuity and bilateral mydriasis. Two days later, they developed eyelid ptosis, asymmetric dysfunction of the extraocular muscles and vomiting.

DISCUSSION

The presence of a paralysis of accommodation, with bilateral mydriasis that reacts to pilocarpine, makes it necessary to consider botulism as a possible cause.

摘要

引言

肉毒中毒目前是一种罕见疾病,肉毒杆菌毒素会导致进行性肌肉麻痹,可因呼吸肌衰竭而致死。

临床病例

两名兄弟均沉迷于可卡因,因近视力下降和双侧瞳孔散大前往急诊科。两天后,他们出现眼睑下垂、眼球外肌不对称功能障碍及呕吐症状。

讨论

存在调节麻痹,伴有对毛果芸香碱有反应的双侧瞳孔散大,这使得有必要将肉毒中毒视为可能的病因。

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