Villegas Fernández F R, Callol Sánchez L, Moreno Muro M, Cuevas Ibáñez A, Gómez de Terreros F J
Servicio de Aparato Respiratorio, Hospital del Aire, Madrid.
Rev Clin Esp. 1991 Apr;188(7):358-61.
A 50 year old man, affected by a Wegener's granulomatosis limited to lung, is presented. The indirect immunofluorescence test for "Anticytoplasmic Antibodies" (ACPA) was negative and we got the definitive diagnostic by the histological study from thoracotomy and biopsy samples. We started treatment with trimethoprim-sulfamethoxazole and a good evolution with an adequate clinical control, x-ray study and blood test was obtained. Some aspects of the value of the ACPA as diagnostic and activity markers of the disease and also the use of an antimicrobial agent on the treatment of this nosological entity are discussed.
本文报告了一名50岁男性患者，患有局限于肺部的韦格纳肉芽肿。“抗细胞质抗体”（ACPA）的间接免疫荧光检测为阴性，我们通过开胸手术和活检样本的组织学研究获得了明确诊断。我们开始使用甲氧苄啶-磺胺甲恶唑进行治疗，并取得了良好的进展，临床得到充分控制，X线检查和血液检查结果良好。本文讨论了ACPA作为该疾病诊断和活动标志物的价值的一些方面，以及抗菌药物在该疾病实体治疗中的应用。
