[肾癌继发异时性甲状腺转移。病例报告]
[Metachronic thyroid metastasis secondary to renal carcinoma. Case report].
作者信息
García-Olaverri Rodríguez Jorge, Villafruela Mateo Ainara, Azurmendi Arin Igor, Olano Grasa Iban, Llarena Ibarguren Roberto, Pertusa Peña Carlos
机构信息
Servicio de Urología, Hospital de Cruces, Baracaldo, España.
出版信息
Arch Esp Urol. 2007 Jul-Aug;60(6):697-9. doi: 10.4321/s0004-06142007000600015.
OBJECTIVE
We report the case of the patient with metachronic thyroid metastasis of a renal adenocarcinoma.
METHODS
61-year-old patient with the diagnosis of renal adenocarcinoma treated by radical nephrectomy (stage pT3bpN0M0) and subsequent interleukin-2 for twelve months presenting four years after surgery with a thyroid nodule displacing the trachea laterally, requiring left hemithyroidectomy.
RESULTS
Pathology reported a lesion made of clear cytoplasm tumor cells, with marked atypia and anaplastic areas, compatible with clear cell renal adenocarcinoma.
CONCLUSIONS
Thyroid metastases are extremely rare, being renal tumors the most frequent origin. They present as painless nodules, cold in gammagram, with normal thyroid hormones. The treatment of choice is surgical excision, with a better prognosis the longer the time between the primary and the appearance of metastasis.
目的
我们报告一例肾腺癌发生异时性甲状腺转移的患者。
方法
一名61岁被诊断为肾腺癌的患者，接受了根治性肾切除术（pT3bpN0M0期），随后接受了十二个月的白细胞介素-2治疗，术后四年出现甲状腺结节并将气管向外侧推移，需要行左侧甲状腺叶切除术。
结果
病理报告显示病变由透明细胞质肿瘤细胞构成，具有明显异型性和间变区域，符合透明细胞肾腺癌。
结论
甲状腺转移极为罕见，肾肿瘤是最常见的原发部位。它们表现为无痛性结节，γ闪烁扫描显示为冷结节，甲状腺激素水平正常。治疗的选择是手术切除，原发肿瘤与转移灶出现之间的时间间隔越长，预后越好。
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