Carmelino Janine, Tavares Ana Paula, Crespo Ana, Coutinho José Mário, Lázaro António, Ribeiro Vasco, Barroso Eduardo
Serviço de Cirurgia Geral. Hospital de Curry Cabral. Centro Hospitalar de Lisboa Central. Lisboa. Portugal.
Serviço de Anatomia Patológica. Hospital de Curry Cabral. Centro Hospitalar de Lisboa Central. Lisboa. Portugal.
Acta Med Port. 2016 Nov;29(11):755-758. doi: 10.20344/amp.7277. Epub 2016 Nov 30.
Clear cell renal carcinoma metastases to the thyroid gland are rare and only diagnosable after an immunohistochemistry analysis of the histological sample. The purpose of this article is to report a case of thyroid metastasis as the initial presentation of a clear cell renal carcinoma.
Male patient with a solid nodule in the left lobe of the thyroid, 5.3 cm in diameter, suspicious of malignancy, for which a total thyroidectomy with central compartment lymphadenectomy was performed. Histology revealed two clear cell renal carcinoma metastases. After evaluation of the kidney, the patient underwent radical nephrectomy four months later.
What makes this case interesting is that thyroid metastases as the initial presentation of renal cell carcinoma are rare, but if treated early, a 'double surgical resection' is possible, leading to a 5 year survival rate of 80%.
透明细胞肾细胞癌转移至甲状腺极为罕见，仅在对组织样本进行免疫组化分析后才能确诊。本文旨在报告一例以甲状腺转移为首发表现的透明细胞肾细胞癌病例。
一名男性患者，甲状腺左叶有一个直径5.3厘米的实性结节，怀疑为恶性，遂行甲状腺全切术及中央区淋巴结清扫术。组织学检查发现两处透明细胞肾细胞癌转移灶。对肾脏进行评估后，患者在四个月后接受了根治性肾切除术。
该病例的有趣之处在于，甲状腺转移作为肾细胞癌的首发表现较为罕见，但如果早期治疗，可行“双手术切除”，5年生存率可达80%。
