腹腔镜子宫骶骨神经切断术联合或不联合骶前神经切除术治疗原发性痛经的前瞻性疗效分析

Laparoscopic uterosacral nerve ablation with and without presacral neurectomy in the treatment of primary dysmenorrhea: a prospective efficacy analysis.

作者信息

Juang Chi-Mou, Chou Pesus, Yen Ming-Shien, Horng Huann-Cheng, Twu Nae-Fong, Chen Chih-Yao

机构信息

Division of General Gynecology, Department of Obstetrics and Gynecology, Veterans General Hospital, and Institution of Epidemiology, College of Public Health, National Yang-Ming University, Taipei, Taiwan.

出版信息

J Reprod Med. 2007 Jul;52(7):591-6.

PMID:17847756

Abstract

OBJECTIVE

To evaluate the efficacy of laparoscopic uterosacral nerve (LUNA) alone vs. LUNA plus presacral neurectomy (PN) in the treatment of primary dysmenorrhea.

STUDY DESIGN

Seventy-four patients were randomly allocated to LUNA alone or LUNA plus PN. Evaluation of severity of menstrual pain was based on multidimensional scoring.

RESULTS

Sixty-seven patients were eligible for analysis (35 LUNA alone, 32 LUNA plus PN). Baseline demographic features were comparable between the 2 groups. There was no difference between them in the proportion of improvement in dysmenorrhea at 3 months of follow-up (69% for LUNA vs. 73% for LUNA plus PN, p = 0.923), and the results were maintained at 6 and 12 months of follow-up. More surgical complications were found in the LUNA plus PN group.

CONCLUSION

For patients with primary dysmenorrhea, LUNA plus PN has no additive therapeutic advantage over LUNA alone, and more surgical complications may be encountered.

摘要

目的

评估单纯腹腔镜子宫骶骨神经切除术（LUNA）与LUNA联合骶前神经切除术（PN）治疗原发性痛经的疗效。

研究设计

74例患者被随机分配至单纯LUNA组或LUNA联合PN组。基于多维度评分评估痛经严重程度。

结果

67例患者符合分析条件（35例单纯LUNA组，32例LUNA联合PN组）。两组的基线人口统计学特征具有可比性。随访3个月时，两组痛经改善比例无差异（单纯LUNA组为69%，LUNA联合PN组为73%，p = 0.923），且在随访6个月和12个月时结果保持不变。LUNA联合PN组发现更多手术并发症。