Fuster Siebert M, Rodríguez Núñez A, Camino López M A, Castro Gago M
Departamento de Pediatría y Medicina, Hospital General de Galicia, Santiago de Compostela.
Rev Clin Esp. 1991 Nov;189(8):355-8.
The authors studied the ECGs of 21 boys with Duchenne's progressive muscular dystrophy (group D) aged from 8 months to 10.5 years. They were compared with 21 age matched healthy boys. There were no statistical significant differences between both groups on maximal or minimal heart rates, nor on their subtractions. There were no differences between the electrical axis of P, QRS or T waves in the frontal plane, nor in the duration or amplitude of P waves. R wave in V1 had 1.06 +/- 0.38 (mean +/- 1 standard deviation) mV in group D, and 0.62 +/- 0.29 mV in group C (p less than 0.001). R/S ratio in V1 was 1.24 +/- 0.53 in group D, and 0.70 +/- 0.50 in group C (p less than 0.01). Q wave in V6 had 0.27 +/- 0.18 mV in group D, and 0.13 +/- 0.09 mV in group C (p less than 0.01). Q/R ratio in V6 was 0.19 +/- 0.14 in group D, and 0.09 +/- 0.047 in group C (p less than 0.01). Sensibility, specificity, positive predictive value, and negative predictive values for signs over 75 percentile (Davignon standards) were: for R wave in V1 71.4%, 76.2%, 75%, and 72.7%; for R/S ratio in V1 71.4%, 76.2%, 75% and 72.7%; for Q wave in V6 38.1%, 85.7%, 72.7%, and 58%.
作者研究了21名年龄在8个月至10.5岁之间的杜兴氏进行性肌营养不良男孩（D组）的心电图。将他们与21名年龄匹配的健康男孩进行比较。两组在最大或最小心率及其差值方面均无统计学显著差异。额面P、QRS或T波的电轴，以及P波的持续时间或振幅均无差异。D组V1导联的R波为1.06±0.38（平均值±1标准差）mV，C组为0.62±0.29 mV（p<0.001）。D组V1导联的R/S比值为1.24±0.53，C组为0.70±0.50（p<0.01）。D组V6导联的Q波为0.27±0.18 mV，C组为0.13±0.09 mV（p<0.01）。D组V6导联的Q/R比值为0.19±0.14，C组为0.09±0.047（p<0.01）。超过第75百分位数（达维农标准）体征的敏感性、特异性、阳性预测值和阴性预测值分别为：V1导联R波71.4%、76.2%、75%和72.7%；V1导联R/S比值71.4%、76.2%、75%和72.7%；V6导联Q波38.1%、85.7%、72.7%和58%。
