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冠状动脉手术中的通过时间血流测定法——移植物验证的重要工具。

Transit time flowmetry in coronary surgery--an important tool in graft verification.

作者信息

Mujanović Emir, Kabil Emir, Bergsland Jacob

机构信息

Cardiovascular Clinic Tuzla, University Clinics Centre, Faculty of Medicine, Trnovac bb 75 000 Tuzla, Bosnia and Herzegovina.

出版信息

Bosn J Basic Med Sci. 2007 Aug;7(3):275-8. doi: 10.17305/bjbms.2007.3059.

Abstract

The aim of this study was to analyze the Transit time flow measurement (TTFM) experience in the first 1000 CABG operations. First 1000 patients had coronary artery bypass grafting (CABG) performed in Cardiovascular Clinic, University Clinical Centre Tuzla, Bosnia and Herzegovina, between September, 1998 and September, 2003. CABG without use of cardiopulmonary bypass (CPB)-(OPCAB) was used as the preferential surgical method both because this method is reported to have equal or better results than CABG with use of CPB (ONCAB), and because of the significant cost savings realized. TTFM was routinely used in all grafts as a quality assurance measure. Criteria for a poor functioning graft were: low mean flow (MF), pulsatility index (PI) above 5 and a poor diastolic flow pattern. When no reversible cause of poor TTFM results were identified the graft was revised. A total of 1394 grafts in OPCAB group and 1478 in ONCAB group were performed. A total of 38 grafts (2,72%) in 37 patients (7,07%) were revised in OPCAB group, and 26 grafts (1,75%) in 26 patients (5,45%) in ONCAB group. 1 patient in OPCAB group needed 2 graft revisions. Graft revisions were more common in OPCAB, but with no significant difference (p=0,1035). The most frequently revised graft was LAD graft in both groups. Although the percentage of grafts revised are relatively low, it is still very important to record TTFM. More than 5% of patients in both groups needed graft revision. Although TTFM does not guarantee that grafts will stay open for a prolonged period of time we certainly believe that grafts that are occluded at the time of surgery will continue to stay occluded. TTFM is especially critical in OPCAB surgery where the technical challenge of grafting is higher then in ONCAB.

摘要

本研究的目的是分析在前1000例冠状动脉旁路移植术(CABG)手术中的渡越时间血流测量(TTFM)经验。1998年9月至2003年9月期间,波斯尼亚和黑塞哥维那图兹拉大学临床中心心血管科对首批1000例患者进行了冠状动脉旁路移植术(CABG)。非体外循环冠状动脉旁路移植术(OPCAB)被用作优先手术方法,这是因为据报道该方法与体外循环冠状动脉旁路移植术(ONCAB)相比具有相同或更好的效果,并且还能显著节省成本。TTFM作为一种质量保证措施,常规用于所有移植物。移植物功能不良的标准为:平均血流(MF)低、搏动指数(PI)高于5以及舒张期血流模式不佳。当未发现导致TTFM结果不佳的可逆原因时,对移植物进行修订。OPCAB组共进行了1394例移植物手术,ONCAB组共进行了1478例。OPCAB组37例患者(7.07%)中的38例移植物(2.72%)进行了修订,ONCAB组26例患者(5.45%)中的26例移植物(1.75%)进行了修订。OPCAB组有1例患者需要进行2次移植物修订。移植物修订在OPCAB中更为常见,但无显著差异(p = 0.1035)。两组中最常修订的移植物均为左前降支(LAD)移植物。尽管修订移植物的百分比相对较低,但记录TTFM仍然非常重要。两组中超过5%的患者需要进行移植物修订。尽管TTFM不能保证移植物在较长时间内保持通畅,但我们坚信在手术时闭塞的移植物将继续保持闭塞状态。TTFM在OPCAB手术中尤为关键,因为其移植技术挑战高于ONCAB。

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