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移植血管血流测量技术在微创冠状动脉旁路移植术中吻合口质量评估中的作用。

Role of graft flow measurement technique in anastomotic quality assessment in minimally invasive CABG.

作者信息

Jaber S F, Koenig S C, BhaskerRao B, VanHimbergen D J, Cerrito P B, Ewert D J, Gray L A, Spence P A

机构信息

Department of Surgery, University of Louisville, School of Medicine, Kentucky, USA.

出版信息

Ann Thorac Surg. 1998 Sep;66(3):1087-92. doi: 10.1016/s0003-4975(98)00752-8.

Abstract

BACKGROUND

Anastomotic quality is currently the critical issue in minimally invasive coronary surgery. Although little is known about its effectiveness, surgeons routinely assess grafts intraoperatively using flow probes. This study was designed to determine whether mean flow and the pattern of flow tracing in internal mammary artery grafts obtained with a transit-time flow probe are reliable indicators of anastomotic quality.

METHODS

Mongrel dogs (n = 14, 30 to 35 kg) underwent off-pump left, right, or left and right internal mammary artery to left anterior descending artery anastomosis (23 grafts). Moderate to severe degrees of stenosis were created at the anastomosis by an additional suture. Internal mammary artery graft flow was measured before and after the stenosis was created with the left anterior descending artery occluded. Angiography was performed at random postoperatively to validate the degree of stenosis. Mean flow and flow tracing morphology were compared under various degrees of stenosis.

RESULTS

There were no significant differences in mean graft flow or the morphology of the flow tracing between patent (<15%), mild (<25%), moderate (<50%), and moderately severe (<75%) stenosis. However, mean graft flow decreased (p < 0.05) with severe stenosis (>75%).

CONCLUSIONS

Although differences in mean graft flow and graft flow morphology were detectable in anastomoses with severe stenosis (>75%), they were indistinguishable in anastomoses with mild (<25%) to moderately severe (<75%) stenosis. Flow measurement techniques are valuable tools intraoperatively, but surgeons should exercise caution in their interpretation.

摘要

背景

吻合质量是目前微创冠状动脉手术中的关键问题。尽管对其有效性了解甚少,但外科医生在术中常规使用血流探头评估移植物。本研究旨在确定通过渡越时间血流探头获得的乳内动脉移植物的平均血流和血流追踪模式是否是吻合质量的可靠指标。

方法

杂种犬(n = 14,体重30至35千克)接受非体外循环下左、右或左、右乳内动脉至左前降支动脉吻合术(23个移植物)。通过额外缝合在吻合口处造成中度至重度狭窄。在左前降支动脉闭塞的情况下,在造成狭窄前后测量乳内动脉移植物的血流。术后随机进行血管造影以验证狭窄程度。比较不同程度狭窄下的平均血流和血流追踪形态。

结果

在通畅(<15%)、轻度(<25%)、中度(<50%)和中重度(<75%)狭窄之间,移植物平均血流或血流追踪形态无显著差异。然而,重度狭窄(>75%)时移植物平均血流降低(p < 0.05)。

结论

尽管在重度狭窄(>75%)的吻合口中可检测到移植物平均血流和移植物血流形态的差异,但在轻度(<25%)至中重度(<75%)狭窄的吻合口中无法区分。血流测量技术是术中的宝贵工具,但外科医生在解读时应谨慎。

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