Yörük Ibrahim, Deger Yeter, Mert Handan, Mert Nihat
Department of Chemistry, Faculty of Science and Arts, University of Yuzuncu Yil, Van, 65080, Turkey.
Biol Trace Elem Res. 2007 Jul;118(1):38-42. doi: 10.1007/s12011-007-0023-y.
The serum concentrations of copper, zinc, iron, and cobalt and copper/zinc ratio were investigated in horses infected with equine herpesvirus-1 (EHV-1). Nine horses were naturally infected with the virus and nine healthy horses served as controls. The concentrations of copper, zinc, iron, and cobalt were determined spectrophotometrically in the blood serum of all horses. The results were (expressed in micrograms per deciliters) copper 2.80 +/- 0.34 vs 1.12 +/- 0.44, zinc 3.05 +/- 0.18 vs 0.83 +/- 0.06, iron 2.76 +/- 0.17 vs 3.71 +/- 0.69, cobalt 0.19 +/- 0.37 vs 0.22 +/- 0.45, and copper/zinc ratio 0.72 +/- 0.38 vs 1.41 +/- 0.36 for control vs infected group, respectively. In conclusion, copper and zinc concentrations of the infected group were lower than the control group (p < 0.001), whereas iron concentration and the copper/zinc ratio of the infected group were higher than the control group (p < 0.05 and p < 0.001). The cobalt concentration was not found to be statistically different between two groups. It might be emphasized that copper/zinc ratio was significantly affected by the EHV-1 infection, so it could be taken into consideration during the course of infection.
对感染马疱疹病毒1型（EHV-1）的马匹的血清铜、锌、铁、钴浓度及铜/锌比值进行了研究。9匹马自然感染该病毒，9匹健康马作为对照。采用分光光度法测定所有马匹血清中的铜、锌、铁和钴浓度。结果（以微克每分升表示）为：对照组与感染组相比，铜分别为2.80±0.34对1.12±0.44，锌为3.05±0.18对0.83±0.06，铁为2.76±0.17对3.71±0.69，钴为0.19±0.37对0.22±0.45，铜/锌比值为0.72±0.38对1.41±0.36。总之，感染组的铜和锌浓度低于对照组（p<0.001），而感染组的铁浓度和铜/锌比值高于对照组（p<0.05和p<0.001）。两组间钴浓度未发现有统计学差异。需要强调的是，EHV-1感染对铜/锌比值有显著影响，因此在感染过程中可予以考虑。
