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肢体节段性带状疱疹性轻瘫:三例报告并文献复习

Segmental zoster paresis of limbs: report of three cases and review of literature.

作者信息

Kawajiri Sumihiro, Tani Momo, Noda Kazuyuki, Fujishima Kenji, Hattori Nobutaka, Okuma Yasuyuki

机构信息

Department of Neurology, Juntendo University Shizuoka Hospital, Shizuoka, Japan.

出版信息

Neurologist. 2007 Sep;13(5):313-7. doi: 10.1097/NRL.0b013e31811e9d6d.

Abstract

OBJECTIVES

Segmental zoster paresis is a relatively rare complication characterized by focal motor weakness, which may occur in limbs affected by herpes zoster. We demonstrate the clinical characteristics of segmental zoster paresis by reviewing the cases of 138 patients, including 3 of our patients.

CASE REPORT AND REVIEW SUMMARY

We report 3 patients with zoster paresis of the limbs. Patients 1 and 3 showed motor weakness in the left shoulder and arm after developing a herpetic rash in the left C5-C6 dermatomes. Patient 2 showed weakness in the right thigh and groin after a right L2-L3 herpetic eruption. The electromyograms of all 3 patients showed abnormal spontaneous activity in the affected muscles. Intravenous acyclovir and corticosteroid pulse therapy were added to oral antiviral drugs for patients 1 and 2. All 3 patients recovered favorably. Our review of the literature revealed that antiviral treatment may prevent the occurrence of zoster paresis; however, there is insufficient evidence to show what treatment hastens recovery from zoster paresis.

CONCLUSIONS

Segmental zoster paresis is still underrecognized by neurologists. Awareness of this disorder is important because it may eliminate unnecessary invasive investigations and lead to appropriate treatment. Further studies on the treatment are necessary.

摘要

目的

节段性带状疱疹性轻瘫是一种相对罕见的并发症,其特征为局灶性运动无力,可发生于带状疱疹累及的肢体。我们通过回顾138例患者(包括我们的3例患者)的病例来阐述节段性带状疱疹性轻瘫的临床特征。

病例报告及综述总结

我们报告3例肢体带状疱疹性轻瘫患者。患者1和患者3在左侧C5 - C6皮节出现疱疹性皮疹后,左侧肩部和手臂出现运动无力。患者2在右侧L2 - L3疱疹发作后,右侧大腿和腹股沟出现无力。所有3例患者的肌电图均显示受累肌肉有异常自发电活动。患者1和患者2在口服抗病毒药物基础上加用了静脉注射阿昔洛韦和皮质类固醇脉冲疗法。所有3例患者均恢复良好。我们对文献的回顾显示,抗病毒治疗可能预防带状疱疹性轻瘫的发生;然而,尚无足够证据表明何种治疗可加速带状疱疹性轻瘫的恢复。

结论

节段性带状疱疹性轻瘫仍未得到神经科医生的充分认识。认识这种疾病很重要,因为它可以避免不必要的侵入性检查并促使进行适当治疗。有必要对该治疗进行进一步研究。

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