Meurer M, Rehberger P
Dermatologie am Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Hautarzt. 2007 Oct;58(10):851-7. doi: 10.1007/s00105-007-1404-z.
The therapy of systemic sclerosis (SSc) remains a challenge for dermatology, rheumatology, internal medicine, and other disciplines. Organ involvement, above all kidney and lungs, is a key therapeutic issue. The current developments in organ-specific therapy are the main topic of the article. Finally, possibilities of disease-modifying drugs and value of HSCT are discussed.
系统性硬化症(SSc)的治疗仍然是皮肤科、风湿病学、内科及其他学科面临的一项挑战。器官受累,尤其是肾脏和肺部受累,是一个关键的治疗问题。本文的主要主题是器官特异性治疗的当前进展。最后,讨论了改善病情药物的可能性以及造血干细胞移植(HSCT)的价值。