Brady Richard R W, Bandari Mark, Kerssens Jan J, Paterson-Brown Simon, Parks Rowan W
Academic Coloproctology, 4th Floor MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh, Scotland EH4 2XU.
World J Surg. 2007 Nov;31(11):2111-6. doi: 10.1007/s00268-007-9218-9.
Splenic trauma is a common organ injury following blunt abdominal trauma. In order to establish the contemporary epidemiology of blunt splenic trauma in Scotland and to detect risk factors associated with patient outcomes, analysis of a multi-center database of trauma patients was performed.
The study used data from a prospectively collated multicenter trauma database containing the details of 52,215 trauma patients admitted to participating Scottish hospitals over an 11-year period.
672 (1.3%) patients (530 males, 142 females) with splenic trauma were identified; of them, 579 (86.2%) had blunt trauma and 93 (13.8%) had penetrating trauma. The mean age of patients with blunt splenic trauma was 35.7 years (33.8 years for males, 42.0 years for females). Increasing age and female sex was significantly associated with mortality. The most common mechanism for injury was road traffic accidents (71%). In the series, 93.8% of patients had concomitant injuries including head injuries (46.5%), thoracic injuries (37.7%) and liver injuries (30%). A total of 299 (51.6%) patients proceeded to laparotomy, and 256 (44.2%) patients required ICU support. The overall mortality was 33.5%, and the median Injury Severity Score was 48 in patients who died, compared to 22 in those who survived. Increased mortality was associated with concomitant aortic, cardiac, or abdominal injuries. A number of independent risk factors were associated with increased risk of mortality, including concomitant injuries, increased age, and increased Injury Severity Score.
The incidence of splenic trauma is low, but it accounts for significant mortality. Outcome in the present study was worse in those with advanced age and associated injuries.
脾外伤是钝性腹部外伤后常见的器官损伤。为了确立苏格兰钝性脾外伤的当代流行病学情况并检测与患者预后相关的危险因素,我们对一个多中心创伤患者数据库进行了分析。
本研究使用了一个前瞻性整理的多中心创伤数据库中的数据,该数据库包含了11年间入住参与研究的苏格兰医院的52215名创伤患者的详细信息。
共识别出672例(1.3%)脾外伤患者(男性530例,女性142例);其中,579例(86.2%)为钝性外伤,93例(13.8%)为穿透性外伤。钝性脾外伤患者的平均年龄为35.7岁(男性33.8岁,女性42.0岁)。年龄增长和女性性别与死亡率显著相关。最常见的损伤机制是道路交通事故(71%)。在该系列中,93.8%的患者有合并伤,包括头部损伤(46.5%)、胸部损伤(37.7%)和肝脏损伤(30%)。共有299例(51.6%)患者接受了剖腹手术,256例(44.2%)患者需要重症监护病房支持。总体死亡率为33.5%,死亡患者的损伤严重度评分中位数为48分,而存活患者为22分。死亡率增加与合并主动脉、心脏或腹部损伤有关。一些独立危险因素与死亡风险增加有关,包括合并伤、年龄增加和损伤严重度评分增加。
脾外伤的发生率较低,但死亡率较高。本研究中,高龄和合并伤患者的预后较差。