Heider Dirk, Kitze Katharina, Zieger Margrit, Riedel-Heller Steffi G, Angermeyer Matthias C
Health Economics Research Unit, Department of Psychiatry, University of Leipzig, Johannisallee 20, 04317 Leipzig, Germany.
Qual Life Res. 2007 Nov;16(9):1453-60. doi: 10.1007/s11136-007-9255-8. Epub 2007 Sep 12.
Objectives of this study are (1) to compare health-related quality of life (HRQOL) of patients after lumbar disc surgery with reference data from the German general population; (2) to examine whether changes in HRQOL occur over time; (3) to investigate associations between HRQOL and socio-demographic and health-related factors.
The study sample consisted at baseline of 189 patients who underwent lumbar disc surgery. Baseline assessment was carried out 1-4 days after surgery, the first follow-up 2 months, the second follow-up 6 months after surgery. HRQOL was assessed by means of the WHOQOL-BREF.
During follow-up, patients showed significant improvement in "physical well being" and "overall quality of life." However, it did not reach the level of the general population at any assessment point. There was also a slight improvement of "psychological well being." The domains "social relationships" and "environment" remained unchanged and showed persistently higher scores than the general population. Cohabitating was positively associated with QoL. Negatively associated were unemployment, part-time employment, desire for early retirement, higher intensity of pain and depression.
Supplementing physical rehabilitation by psychosocial interventions may help improve patients' HRQOL.
本研究的目的是：（1）将腰椎间盘手术后患者的健康相关生活质量（HRQOL）与德国普通人群的参考数据进行比较；（2）检查HRQOL是否随时间发生变化；（3）调查HRQOL与社会人口学及健康相关因素之间的关联。
研究样本在基线时包括189例行腰椎间盘手术的患者。基线评估在术后1 - 4天进行，首次随访在术后2个月，第二次随访在术后6个月。HRQOL通过世界卫生组织生活质量简表（WHOQOL - BREF）进行评估。
在随访期间，患者在“身体健康”和“总体生活质量”方面有显著改善。然而，在任何评估点均未达到普通人群的水平。“心理健康”也有轻微改善。“社会关系”和“环境”领域保持不变，且得分持续高于普通人群。同居与生活质量呈正相关。与生活质量呈负相关的因素有失业、兼职工作、提前退休意愿、较高的疼痛强度和抑郁。
通过心理社会干预补充身体康复可能有助于改善患者的HRQOL。
