Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Spine (Phila Pa 1976). 2011 Dec 1;36(25):2147-51. doi: 10.1097/BRS.0b013e3182054595.
This is a prospective cohort study with serial imaging.
We set out to determine the incidence of symptomatic and asymptomatic same-level recurrent disc herniation and assess their effect on 2-year outcome.
The reported incidence of symptomatic same-level recurrent disc herniation after lumbar discectomy varies widely in retrospective studies. To date, the incidence of radiographic same-level recurrent disc herniation has not been studied prospectively with sequential imaging. Furthermore, the clinical relevance of recurrent disc herniation on magnetic resonance imaging (MRI) after discectomy remains unknown, particularly in patients with poorly specific pain after surgery.
One hundred eight patients undergoing lumbar discectomy for a single-level herniated disc at five institutions were prospectively observed for 2 years. Computed tomography (CT) and MRI of the lumbar spine were obtained every 3 months to assess reherniation and disc height loss. Leg and back pain visual analog scale (VAS), Oswestry Disability Index (ODI), and quality of life (SF-36 physical component) were assessed 3, 6, 12, and 24 months after surgery.
No patients demonstrated residual disc on postoperative MRI. By 2 years after discectomy, 25 (23.1%) patients had demonstrated radiographic evidence of recurrent disc herniation at the level of prior discectomy on serial imaging (mean ± SD, 11.8 ± 8.3 months after surgery). Radiographic disc herniation was asymptomatic in 14 (13%) patients and symptomatic in 11 (10.2%) patients. The occurrence of symptomatic recurrent disc herniation was associated with worse 2-year leg pain (VAS-LP, P=0.002) and disability (ODI, P=0.036) but not quality of life (SF-36) or disc height loss. The occurrence of asymptomatic reherniation was not associated with disc height loss or any outcome measure (VAS, ODI, and SF-36) by 2 years.
Nearly one-fourth of patients undergoing lumbar discectomy demonstrated radiographic evidence of recurrent disc herniation at the level of prior surgery, the majority of which were asymptomatic. Asymptomatic disc herniation was not associated with clinical consequences by 2 years. Clinically silent recurrent disc herniation is common after lumbar discectomy. When obtaining MRI evaluation within the first 2 years of discectomy, providers should expect that radiographic evidence of reherniation may be encountered and that treatment should be considered only when correlating radicular symptoms exist.
这是一项具有连续影像学的前瞻性队列研究。
我们旨在确定同节段复发性椎间盘突出症的症状性和无症状性发生率,并评估其对 2 年结果的影响。
回顾性研究中,腰椎间盘切除术后症状性同节段复发性椎间盘突出症的报告发生率差异很大。迄今为止,尚未前瞻性地通过连续影像学检查研究同节段复发性椎间盘突出症的放射学发生率。此外,椎间盘切除术后磁共振成像(MRI)上复发性椎间盘突出症的临床相关性仍不清楚,尤其是在术后疼痛特异性较差的患者中。
在五个机构中,对 108 例因单节段椎间盘突出症而行腰椎间盘切除术的患者进行前瞻性观察 2 年。每 3 个月进行腰椎 CT 和 MRI 检查,以评估再突出和椎间盘高度丢失。术后 3、6、12 和 24 个月,评估腿部和背部疼痛视觉模拟量表(VAS)、Oswestry 残疾指数(ODI)和生活质量(SF-36 生理成分)。
术后 MRI 上无患者显示残余椎间盘。腰椎间盘切除术后 2 年,25 例(23.1%)患者在连续影像学检查中显示出先前椎间盘切除术后水平的放射学证据表明存在复发性椎间盘突出症(术后 11.8±8.3 个月,平均±SD)。14 例(13%)患者的椎间盘突出症为无症状,11 例(10.2%)患者为症状性。症状性复发性椎间盘突出症的发生与 2 年腿部疼痛(VAS-LP,P=0.002)和残疾(ODI,P=0.036)更差相关,但与生活质量(SF-36)或椎间盘高度丢失无关。无症状再突出的发生与 2 年时的椎间盘高度丢失或任何结局测量(VAS、ODI 和 SF-36)无关。
近四分之一接受腰椎间盘切除术的患者在先前手术水平显示出放射学证据表明存在复发性椎间盘突出症,其中大多数为无症状。2 年内,无症状椎间盘突出症与临床后果无关。腰椎间盘切除术后,临床无症状的复发性椎间盘突出症很常见。在椎间盘切除术后的前 2 年内进行 MRI 评估时,医生应预计可能会发现影像学上的再突出,并仅在出现神经根症状时才考虑进行治疗。