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川崎病患儿中人博卡病毒的检测

Detection of human bocavirus in children with Kawasaki disease.

作者信息

Catalano-Pons C, Giraud C, Rozenberg F, Meritet J-F, Lebon P, Gendrel D

机构信息

Service de Pédiatrie Générale, Hôpital Saint-Vincent-de-Paul, Paris, France.

出版信息

Clin Microbiol Infect. 2007 Dec;13(12):1220-2. doi: 10.1111/j.1469-0691.2007.01827.x. Epub 2007 Sep 10.

DOI:10.1111/j.1469-0691.2007.01827.x
PMID:17850342
Abstract

Human bocavirus (HboV) is an emerging virus that has been implicated as a cause of acute upper and lower respiratory tract infection in children. As no serological assay is available, PCR was used to screen nasopharyngeal, serum or stool samples from 16 patients with Kawasaki disease for HBoV nucleic acid. HBoV was identified by PCR in five (31.2%) patients, suggesting that this emerging virus may also play a pathogenic role in some cases of Kawasaki disease.

摘要

人博卡病毒(HboV)是一种新出现的病毒,被认为是儿童急性上、下呼吸道感染的病因之一。由于没有血清学检测方法,采用聚合酶链反应(PCR)对16例川崎病患者的鼻咽、血清或粪便样本进行HBoV核酸筛查。通过PCR在5例(31.2%)患者中检测到HBoV,提示这种新出现的病毒在某些川崎病病例中可能也起致病作用。

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