Mandel Corey R, Tong Liang
Structure. 2007 Sep;15(9):1024-6. doi: 10.1016/j.str.2007.08.002.
In an elegant study in this issue of Structure, Balbo and Bohm (2007) report the crystal structure of yeast poly(A) polymerase in a ternary complex with its substrate MgATP and the elongating poly(A) tail, providing molecular insights into the mechanism of polyadenylation.
在本期《结构》杂志上发表的一项出色研究中,巴尔博和博姆(2007年)报告了酵母聚腺苷酸聚合酶与底物MgATP以及正在延伸的聚腺苷酸尾形成的三元复合物的晶体结构,为聚腺苷酸化机制提供了分子层面的见解。