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[马提尼克岛的结直肠癌:20年期间的发病率和死亡率]

[Colorectal cancers in Martinique: incidence and mortality rates over a period of 20 years].

作者信息

Ngasseu P, Dieye M, Veronique-Baudin J, Draganescu C, Dorival M-J, Ossondo M, Smith-Ravin J, Azaloux H

机构信息

Service de médecine nucléaire oncologie, CHU de Fort-de-France, GREFCC, université des Antilles-Guyane, Martinique.

出版信息

Rev Epidemiol Sante Publique. 2007 Oct;55(5):333-8. doi: 10.1016/j.respe.2007.06.001. Epub 2007 Sep 11.

Abstract

BACKGROUND

Colorectal cancer is the second leading cause of cancer death in Western countries, with an incidence progressively increasing in developing countries. Worldwide, colorectal cancer is the second and third leading cause of death by cancer in females and males respectively. According to the Martinique Cancer Register data, colorectal cancer is the second leading cause of death by cancer in women, and the fourth in men. Colorectal cancer exhibits a variable distribution worldwide. This study was conducted to observe variations in colorectal incidence and mortality rates observed over a twenty-year period. Such data will be useful for monitoring changing trends related to onset of an organized screening program.

METHOD

Patients with colorectal cancer diagnosed from 1981 to 2000 in Martinique were included in this study. Data are obtained from the Martinique Cancer Register.

RESULTS

The incidence of colorectal cancer in Martinique (16/100,000 and 17/100,000 in the female and male population respectively in the year 2000) is intermediary compared with other countries worlwide. There is a current trend towards increased incidence and mortality. The incidence has increased for cancers localized in the proximal colon, the sigmoid colon and the rectum.

CONCLUSION

The increasing incidence of colorectal cancer in all localisations raises concern in Martinique. A significant predominance of colorectal cancer incidence among the male population in Martinique was not observed. Gender and age do not appear to imply any preferential localisation of colorectal cancer.

摘要

背景

在西方国家,结直肠癌是癌症死亡的第二大主要原因,在发展中国家其发病率也在逐渐上升。在全球范围内,结直肠癌分别是女性和男性癌症死亡的第二和第三大主要原因。根据马提尼克岛癌症登记处的数据,结直肠癌是女性癌症死亡的第二大主要原因,在男性中则排第四。结直肠癌在全球的分布各不相同。本研究旨在观察二十年间结直肠癌发病率和死亡率的变化。这些数据将有助于监测与有组织筛查计划启动相关的变化趋势。

方法

本研究纳入了1981年至2000年在马提尼克岛诊断出的结直肠癌患者。数据来自马提尼克岛癌症登记处。

结果

与世界其他国家相比,马提尼克岛的结直肠癌发病率(2000年女性和男性人口中分别为16/10万和17/10万)处于中等水平。目前存在发病率和死亡率上升的趋势。近端结肠、乙状结肠和直肠部位的癌症发病率有所增加。

结论

马提尼克岛所有部位结直肠癌发病率的上升令人担忧。未观察到马提尼克岛男性人群中结直肠癌发病率有显著优势。性别和年龄似乎并不意味着结直肠癌有任何优先发病部位。

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