内毒素和肾上腺素孵育后小鼠肝细胞膜的腺苷酸环化酶活性
Adenyl cyclase activity of mouse liver membranes after incubation with endotoxin and epinephrine.
作者信息
Donlon M A, Walker R I
出版信息
Experientia. 1976 Feb 15;32(2):179-81. doi: 10.1007/BF01937752.
PMID:178522
Abstract
Adenyl cyclase activity in isolated mouse liver cell membranes was stimulated two-fold by endotoxin. Furthermore, endotoxin inhibited epinephrine induction of adenyl cyclase activity, apparently through interruption of the phospholipid moiety of the enzyme complex.
摘要
内毒素可使分离出的小鼠肝细胞膜中的腺苷酸环化酶活性提高两倍。此外，内毒素明显通过干扰酶复合物的磷脂部分来抑制肾上腺素诱导的腺苷酸环化酶活性。
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