Hahn R G
Department of Anaesthesiology, Huddinge University Hospital, Stockholm, Sweden.
Acta Anaesthesiol Scand. 1991 Oct;35(7):557-67. doi: 10.1111/j.1399-6576.1991.tb03348.x.
The transurethral resection syndrome ("TUR syndrome") is caused by absorption of electrolyte-free irrigating fluid, and consists of symptoms from the circulatory and nervous systems. The clinical picture is inconsistent and the syndrome is easily confused with other acute disorders. Mild forms are common and often go undiagnosed, while severe forms of the TUR syndrome are rare and potentially life-threatening. The pathophysiology is complex but includes four mechanisms: circulatory distress from the rapid absorption of electrolyte-free irrigating fluid, adverse effects of glycine, dilution of the protein and electrolyte concentrations of the body fluids, and disturbance of renal function. The treatment of the TUR syndrome consists of general life support and in specific treatment directed towards hypotension, hyponatraemia and anuria. Methods to lower the uptake of irrigating fluid are widely used and probably reduce the incidence of the TUR syndrome. However, patient safety can be guaranteed only if the absorption is monitored. An irrigating fluid containing tracer amounts of ethanol can be used for this purpose. This permits the uptake of fluid to be indicated by measuring the concentration of ethanol in the patient's exhaled breath.
经尿道切除综合征(“TUR综合征”)由无电解质冲洗液的吸收引起,包括循环系统和神经系统的症状。临床表现不一致,该综合征容易与其他急性疾病混淆。轻度形式常见且常未被诊断出来,而重度TUR综合征则罕见且可能危及生命。其病理生理过程复杂,但包括四种机制:无电解质冲洗液快速吸收导致的循环窘迫、甘氨酸的不良反应、体液中蛋白质和电解质浓度的稀释以及肾功能紊乱。TUR综合征的治疗包括一般生命支持以及针对低血压、低钠血症和无尿的特定治疗。降低冲洗液吸收的方法被广泛使用,可能会降低TUR综合征的发生率。然而,只有在监测吸收情况时才能确保患者安全。为此可使用含有微量乙醇的冲洗液。这使得通过测量患者呼出气体中的乙醇浓度来指示液体的吸收情况成为可能。