Perko G, Perko M J, Jansen E, Secher N H
Department of Anaesthesia, Rigshospitalet, University of Copenhagen, Denmark.
Acta Anaesthesiol Scand. 1991 Oct;35(7):568-71. doi: 10.1111/j.1399-6576.1991.tb03349.x.
Thoracic impedance at 2.5 (TI2.5) and 100 kHz (TI100), central venous pressure (CVP), and body fluid balance were recorded together with rectal temperature and arterial haematocrit in 15 consecutive patients subjected to coronary artery bypass grafting. I.v. fluid and blood were administered in an excess of 3.18 (1.38-9.35) 1 during the operation. TI2.5 decreased from 51.7 (39.2-66.4) to 34.9 (21.1-45.7) ohm (P = 0.001), while TI100 decreased from 41.9 (31.4-55.0) to 30.3 (18.3-40.8) ohm (P = 0.002). CVP, 6 (3-11) mmHg [0.8 (0.4-1.5) kPa], was the same before and after surgery. Temperature decreased during cardiopulmonary bypass from 35.4 (34.1-36.6) to 26.7 (22.9-31.0) degrees C and haematocrit from 39 (34-46)% to a lowest value of 27 (23-32)% (P = 0.0001). A close linear correlation between TI and body fluid balance was observed (TI2.5: r = -0.96, TI100: r = -0.95, P = 0.0001). Corrections of TI for temperature and/or haematocrit improved the correlation between TI and fluid balance to 0.99 (TI2.5) and 0.98 (TI100). The data indicate that changes in thoracic impedance can be used to monitor body fluid balance during cardiac surgery.
对15例连续接受冠状动脉搭桥术的患者,同时记录其2.5kHz(TI2.5)和100kHz(TI100)时的胸段阻抗、中心静脉压(CVP)以及体液平衡情况,并记录直肠温度和动脉血细胞比容。术中静脉输注液体和血液总量超过3.18(1.38 - 9.35)升。TI2.5从51.7(39.2 - 66.4)欧姆降至34.9(21.1 - 45.7)欧姆(P = 0.001),而TI100从41.9(31.4 - 55.0)欧姆降至30.3(18.3 - 40.8)欧姆(P = 0.002)。CVP术前术后均为6(3 - 11)mmHg [0.8(0.4 - 1.5)kPa]。体外循环期间体温从35.4(34.1 - 36.6)℃降至26.7(22.9 - 31.0)℃,血细胞比容从39(34 - 46)%降至最低值27(23 - 32)%(P = 0.0001)。观察到TI与体液平衡之间存在密切的线性相关性(TI2.5:r = -0.96,TI100:r = -0.95,P = 0.0001)。对TI进行温度和/或血细胞比容校正后,TI与体液平衡的相关性提高到0.99(TI2.5)和0.98(TI100)。这些数据表明,胸段阻抗的变化可用于心脏手术期间监测体液平衡。