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超声引导下对胎儿心率异常的早产胎儿进行pH值和血气分析的胎儿血液采样。

Sonography-guided fetal blood sampling for pH and blood gases in premature fetuses with abnormal fetal heart rate traces.

作者信息

Shalev E, Dan U, Yanai N, Weiner E

机构信息

Department of Obstetrics and Gynecology, Central Emek Hospital, Afula, Israel.

出版信息

Acta Obstet Gynecol Scand. 1991;70(7-8):539-42. doi: 10.3109/00016349109007913.

Abstract

In nine pregnancies, remote from term, with an abnormal Non-Stress Test (NST) and Bio-Physical Profile (BPP) of 3 or above, cordocentesis for fetal blood gas analysis was performed. In seven cases an immediate post-partum blood sample was taken from the fetal cord for a similar analysis. The two tests gave very similar results. The results showed fetal acidemia (pH 7.09-7.19 and B.E. -10-15) in 4 cases, followed by immediate delivery. In the remaining 5 cases, normal blood gases were evident (pH 7.28-7.35); despite the abnormal NST, pregnancy was allowed to continue for 2 to 7 weeks, under close supervision. At birth, 2 out of 9 newborns were deemed by the neonatologist suffering from asphyxia. Both belonged to the acidemic group of women who were managed by immediate cesarean section. The other 5 fetuses, which were managed expectantly, had normal post-partum blood gases or Apgar score; none had asphyxia. Fetal blood gas analysis, on samples obtained by cordocentesis, provides useful information that can assist in the management of premature fetuses suspected of being distressed, according to their heart traces. Normal fetal blood gases can identify those fetuses falsely identified by the NST as in distress and thereby spare them unnecessary premature birth with its known complications.

摘要

在9例未足月妊娠中,无应激试验(NST)异常且生物物理评分(BPP)为3分及以上,对其进行了脐血穿刺术以分析胎儿血气。7例在产后立即从胎儿脐带采集血样进行类似分析。两种检测结果非常相似。结果显示4例胎儿存在酸血症(pH值7.09 - 7.19,碱剩余-10至-15),随后立即分娩。其余5例血气正常(pH值7.28 - 7.35);尽管NST异常,但在密切监测下,妊娠得以继续2至7周。出生时,新生儿科医生认为9例新生儿中有2例患有窒息。这2例均属于通过立即剖宫产处理的酸血症组女性。另外5例接受期待治疗的胎儿产后血气或阿氏评分正常;无一例患有窒息。根据胎儿心率监测结果,通过脐血穿刺术获取样本进行胎儿血气分析,可为疑似窘迫的未成熟胎儿的处理提供有用信息。正常的胎儿血气可识别那些被NST错误判定为窘迫的胎儿,从而避免其不必要的早产及其已知的并发症。

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