通过基于SYBR Green的实时逆转录聚合酶链反应首次从一名患有严重肾综合征出血热的患者中检测到多布拉伐汉坦病毒。
First detection of Dobrava hantavirus from a patient with severe haemorrhagic fever with renal syndrome by SYBR Green-based real time RT-PCR.
作者信息
Jakab Ferenc, Sebok Judit, Ferenczi Emoke, Horváth Gyozo, Szucs György
机构信息
Department of Genetics and Molecular Biology, Institute of Biology, University of Pécs, Ifjúság ut 6, H-7624, Pécs, Hungary.
出版信息
Scand J Infect Dis. 2007;39(10):902-6. doi: 10.1080/00365540701387072.
Dobrava hantavirus (DOBV) infection was diagnosed in a previously healthy 46-y-old hunter suffering from severe haemorrhagic fever with renal syndrome (HFRS). Specific IgM antibodies against DOBV were identified by an immunofluorescence assay, while viral nucleic acid was detected by the molecular method, confirming the diagnosis. Our results reveal an existing risk of DOBV transmission to humans in Hungary.
一名先前健康的46岁猎人被诊断感染多布拉伐汉坦病毒（DOBV），患有严重肾综合征出血热（HFRS）。通过免疫荧光测定法鉴定出针对DOBV的特异性IgM抗体，同时通过分子方法检测到病毒核酸，从而确诊。我们的结果揭示了匈牙利存在DOBV传播给人类的风险。
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