Watanabe Tetsuya, Maruyama Satoshi, Maruyama Yukitaka, Kageyama Shinji, Shinbo Hitoshi, Otsuka Atsushi, Ozono Seiichiro
Department of Urology, Maruyama Hospital, Japan.
Scand J Urol Nephrol. 2007;41(6):521-6. doi: 10.1080/00365590701485921.
To determine whether subjective or objective seasonal changes occur in patients with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH).
A total of 31 patients with LUTS were observed for >5 years. Their International Prostate Symptom Score (IPSS), quality of life (QOL) score, maximum flow rate (Qmax), voided volume (VV) a nd post-void residual (PVR) we re measured every month.
Total IPSS, QOL, VV or PVR did not show any seasonal changes between the three seasons: summer (hot season: June to September); winter (cold season: December to March); and spring and fall (comfortable season: April, May, October and November). Furthermore, when the IPSS was examined by dividing it into storage symptoms (frequency, urgency and nocturia) and voiding symptoms (incomplete emptying, intermittency, weak stream and straining), no significant seasonal changes were detected. Only Qmax showed a significant seasonal change, being higher in both the cold season (median 10.4 ml/s) and the comfortable season (median 10.1 ml/s) than in the hot season (median 9.4 ml/s).
It has generally been thought that LUTS worsen in winter. Our results indicate that the IPSS and the QOL score remain nearly constant if they are determined regularly over an extended period of time. Qmax may however be influenced by seasonal changes in temperature.
确定提示良性前列腺增生（BPH）的下尿路症状（LUTS）患者是否存在主观或客观的季节性变化。
共观察了31例LUTS患者5年以上。每月测量他们的国际前列腺症状评分（IPSS）、生活质量（QOL）评分、最大尿流率（Qmax）、排尿量（VV）和残余尿量（PVR）。
在夏季（炎热季节：6月至9月）、冬季（寒冷季节：12月至3月）以及春秋季（舒适季节：4月、5月、10月和11月）这三个季节之间，IPSS总分、QOL、VV或PVR均未显示出任何季节性变化。此外，将IPSS分为储尿症状（尿频、尿急和夜尿）和排尿症状（排尿不尽、尿流中断、尿流无力和排尿费力）进行检查时，未发现明显的季节性变化。只有Qmax显示出显著的季节性变化，寒冷季节（中位数10.4 ml/s）和舒适季节（中位数10.1 ml/s）的Qmax均高于炎热季节（中位数9.4 ml/s）。
一般认为LUTS在冬季会加重。我们的结果表明，如果在较长时间内定期测定，IPSS和QOL评分几乎保持不变。然而，Qmax可能受温度季节性变化的影响。
