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卡拉奇(巴基斯坦)的脑膜炎球菌病疫情:一项针对儿童的研究。

An epidemic of meningococcal disease in Karachi (Pakistan): a study of children.

作者信息

Dure-Samin A, Mubina A, Azra Y

机构信息

Department of Paediatrics Unit-II, Civil Hospital, Karachi, Pakistan.

出版信息

Acta Paediatr Jpn. 1991 Jun;33(3):352-6. doi: 10.1111/j.1442-200x.1991.tb01565.x.

DOI:10.1111/j.1442-200x.1991.tb01565.x
PMID:1785331
Abstract

A prospective study of 112 cases of epidemic meningococcal infection in the paediatric population is presented. The natural course of the disease, its complications, prognostic factors and therapeutic agents were studied. The cases were graded according to fixed criteria of severity which correlated well with the outcome of the disease. The gram-stain of the CSF was a sensitive and a quick method of diagnosis and crystalline penicillin a cost-effective therapy giving a good response within 48 hours in 90% of the cases.

摘要

本文呈现了一项针对112例儿童流行性脑膜炎球菌感染病例的前瞻性研究。对该疾病的自然病程、并发症、预后因素及治疗药物进行了研究。根据与疾病转归密切相关的固定严重程度标准对病例进行分级。脑脊液革兰氏染色是一种敏感且快速的诊断方法,结晶青霉素是一种性价比高的治疗药物,90%的病例在48小时内对此有良好反应。

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引用本文的文献

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Review of the cost effectiveness of immunisation strategies for the control of epidemic meningococcal meningitis.控制流行性脑膜炎球菌性脑膜炎免疫策略的成本效益综述
Pharmacoeconomics. 2005;23(4):333-43. doi: 10.2165/00019053-200523040-00004.
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