Nassar Anwar H, Salti Ibrahim, Makarem Nisrine N, Usta Ihab M
Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon.
Am J Perinatol. 2007 Sep;24(8):481-2. doi: 10.1055/s-2007-986696. Epub 2007 Sep 12.
Symptomatic hypocalcemia has been reported infrequently in association with magnesium sulfate (MgSO (4)) tocolytic therapy. We report a 38-year-old woman who presented in preterm labor at 24 3/7 weeks. Twenty hours after starting MgSO (4), she developed chest pain. Studies revealed therapeutic serum Mg level, total serum calcium (Ca) = 5.5 mg/dL, 24-hour urine Ca = 763.9 mg, and low serum uric acid and phosphate levels. All studies corrected day 1 postpartum; urine Ca level corrected on day 2. Even short courses of MgSO (4) can result in severe hypocalcemia, raising the question of whether Ca levels should be routinely monitored.
有症状的低钙血症与硫酸镁（MgSO₄）的保胎治疗相关的报道较少。我们报告了一名38岁的女性，她在孕24⁺³/₇周时出现早产。开始使用MgSO₄ 20小时后，她出现胸痛。检查发现血清镁水平处于治疗范围，血清总钙（Ca）=5.5mg/dL，24小时尿钙=763.9mg，血清尿酸和磷酸盐水平较低。所有检查结果在产后第1天恢复正常；尿钙水平在第2天恢复正常。即使是短期使用MgSO₄也可能导致严重的低钙血症，这引发了是否应常规监测钙水平的问题。
