Berlly Michael, Shem Kazuko
Santa Clara Valley Medical Center, 751 S. Bascom Avenue, San Jose, CA 95128, USA.
J Spinal Cord Med. 2007;30(4):309-18. doi: 10.1080/10790268.2007.11753946.
Respiratory complications are the most common cause of morbidity and mortality in acute spinal cord injury (SCI), with an incidence of 36% to 83%. Eighty percent of deaths in patients hospitalized with cervical SCI are secondary to pulmonary dysfunction, with pneumonia the cause in 50% of the cases. The number of respiratory complications during the acute hospital stay contributes significantly to the length of hospital stay and cost. Four factors (use of mechanical ventilation, pneumonia, the need for surgery, and use of tracheostomy) explain nearly 60% of hospital costs and may be as important a predictor of hospital cost as level of injury. Atelectasis (36.4%), pneumonia (31.4%), and ventilatory failure (22.6%) are the most common complications during the first 5 days after injury. Ventilatory failure occurs on average 4.5 days after injury. Transfer to an SCI center specializing in acute management of tetraplegia has been shown to significantly reduce the number of respiratory complications. This review concentrates on the first 5 days after injury, focusing on complications, predictive factors, prevention, and management of those complications.
呼吸并发症是急性脊髓损伤(SCI)发病和死亡的最常见原因,发生率为36%至83%。颈椎SCI住院患者中80%的死亡继发于肺功能障碍,其中50%的病例死因是肺炎。急性住院期间呼吸并发症的数量对住院时间和费用有显著影响。四个因素(机械通气的使用、肺炎、手术需求和气管切开术的使用)解释了近60%的住院费用,并且可能与损伤程度一样是住院费用的重要预测指标。肺不张(36.4%)、肺炎(31.4%)和呼吸衰竭(22.6%)是损伤后前5天最常见的并发症。呼吸衰竭平均发生在损伤后4.5天。转至专门从事四肢瘫痪急性管理的SCI中心已被证明可显著减少呼吸并发症的数量。本综述集中于损伤后的前5天,重点关注并发症、预测因素、预防以及这些并发症的管理。