Prince of Wales Hospital, Sydney, NSW, Australia.
Crit Care Resusc. 2012 Mar;14(1):64-73.
Respiratory complications following cervical spinal cord injury are common and are the leading cause of morbidity and mortality after this type of injury. Impaired mechanics of ventilation, poor cough, increased secretions and bronchospasm predispose to atelectasis, pneumonia and exacerbations of respiratory failure. Prolonged mechanical ventilation and tracheostomy are often required. This review discusses the relevant pathophysiology, various ventilatory strategies and timing of tracheostomy, and examines the evidence surrounding physiotherapeutic and pharmacological treatment options.
颈椎脊髓损伤后的呼吸并发症很常见,是此类损伤后发病率和死亡率的主要原因。通气力学受损、咳嗽无力、分泌物增加和支气管痉挛易导致肺不张、肺炎和呼吸衰竭恶化。通常需要长时间的机械通气和气管切开术。本文综述了相关的病理生理学、各种通气策略和气管切开术时机,并探讨了围绕物理治疗和药物治疗选择的证据。