Yang Dian-hui, Han Jing, Shan Qiu-hua
Acupuncture Department, Affiliated Hospital of Shandong University of TCM, Jinan 250011, China.
Zhongguo Zhen Jiu. 2007 Aug;27(8):569-71.
To probe into the therapeutic effect of ear point combined therapy on common migraine at the remission stage and the mechanism.
Thirty-two cases of common migraine at the remission stage were treated with ear point combined therapy, including blood-letting at ear back, injection of autoblood into Fengchi (GB 20), Yanglingquan (GB 34), and pricking at ear points Nie, Yi-dan (pancreas and gallbladder), Shenmen, etc.. Clinical therapeutic effect was evaluated at the end of one therapeutic course, and calcitonin gene-related peptide (CGRP) and endotheline (ET) were detected before and after treatment, and the CGRP and ET contents were compared with those in 22 normal persons.
The effective rate was 78.1% (P<0.001), CGRP and ET contents had very significant changes after treatment (P<0.01), and CGRP and ET showed negative correlativity (P<0.05).
The ear point combined therapy can regulates the balance between the plasma CGRP and ET in the patient of common migraine and improve vasodilative, vasoconstrictive and endothelial fuctions in the brain, hence stopping pain.
探讨耳穴综合疗法对普通偏头痛缓解期的治疗效果及作用机制。
采用耳穴综合疗法治疗32例普通偏头痛缓解期患者，包括耳背放血、风池（GB20）、阳陵泉（GB34）穴位自血注射及耳穴颞、胰胆、神门等点刺。一个疗程结束后评价临床治疗效果，治疗前后检测降钙素基因相关肽（CGRP）和内皮素（ET），并与22例正常人的CGRP和ET含量进行比较。
有效率为78.1%（P<0.001），治疗后CGRP和ET含量有非常显著变化（P<0.01），且CGRP与ET呈负相关（P<0.05）。
耳穴综合疗法可调节普通偏头痛患者血浆中CGRP与ET的平衡，改善脑内血管舒张、收缩及内皮功能，从而止痛。
