Yang Dian-hui
Department of Acupuncture, Affiliated Hospital of Shandong University of TCM, Jinan 250011, China.
Zhongguo Zhen Jiu. 2009 Mar;29(3):189-91.
To evaluate the therapeutic effect of ear point combined therapy on no-aura migraine at different stages and the mechanism.
Thirty cases of no-aura migraine at different stages were treated with ear point combined therapy, including blood-letting at the ear back, injection of auto-blood into Fengchi (GB 20), Yanglingquan (GB 34), and pricking at ear points Nie (AT2), Yidan (CO11), Shenmen (TF4), etc. Their clinical therapeutic effects were evaluated at the end of one therapeutic course, and substance P (SP) contents were detected before and after treatment.
The clinical effective rate was 86.7%, and the effective rate was 87.5% at the attack stage and 86.4% at the remission stage with no significant difference between the attack stage and the remission stage (P>0.05); after treatment, SP content had significant change as compared with that before treatment (P<0.05, P<0.01), and there was very significant difference in SP content between the attack stage before treatment and the remission stage (P<0.01).
The ear point combined therapy can relieve pain possibly through decreasing plasma SP content, and the SP con tent possibly is one of main factors inducing migraine attack.
评估耳穴综合疗法对不同阶段无先兆偏头痛的治疗效果及作用机制。
对30例不同阶段的无先兆偏头痛患者采用耳穴综合疗法进行治疗，包括耳背放血、风池（GB20）、阳陵泉（GB34）自血注射，以及耳穴颞（AT2）、胰胆（CO11）、神门（TF4）等点刺。在一个疗程结束时评估其临床治疗效果，并检测治疗前后P物质（SP）含量。
临床有效率为86.7%，发作期有效率为87.5%，缓解期有效率为86.4%，发作期与缓解期比较差异无统计学意义（P>0.05）；治疗后，SP含量与治疗前比较有显著变化（P<0.05，P<0.01），治疗前发作期与缓解期SP含量比较有非常显著差异（P<0.01）。
耳穴综合疗法可能通过降低血浆SP含量而缓解疼痛，SP含量可能是诱发偏头痛发作的主要因素之一。
