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[缓释促黄体生成素释放激素类似物(TAP-144SR长效注射剂)治疗或合成雌激素治疗下前列腺癌患者生活质量的比较]

[A comparison of the quality of life of prostatic cancer patients under slow releasing LH-RH analogue (TAP-144SR Depot) treatment or synthetic estrogen treatment].

作者信息

Oishi K, Arai Y, Takeuchi H, Yoshida O

机构信息

Department of Urology, Faculty of Medicine, Kyoto University.

出版信息

Hinyokika Kiyo. 1991 Sep;37(9):1017-22.

PMID:1785408
Abstract

The quality of life (QOL) was studied on 31 prostatic cancer (PC) patients, being followed at our out-patient-clinic during a relapse-free period. Fifteen of them were under treatment with a slow releasing LH-RH analogue (TAP-144 SR Depot) (TAP) and the other 16 prostatic cancer patients with synthetic estrogen (Honvan) (DES). The QOL of 37 benign prostatic hyperplasia (BPH) patients on conservative treatment was also studied. Concerning their general feeling of health, the prostatic cancer patients on TAP treatment felt subjectively better than those on DES. The social life of the patients on TAP or those who had BPH was less affected than that of those on DES. The quality of sexual life was worse for the prostatic cancer patients on both TAP and DES treatment than for the BPH patients.

摘要

对31例前列腺癌(PC)患者的生活质量(QOL)进行了研究,这些患者在我们的门诊接受随访,处于无复发期。其中15例接受缓释促黄体生成素释放激素类似物(TAP - 144 SR Depot)(TAP)治疗,另外16例前列腺癌患者接受合成雌激素(己烯雌酚)(DES)治疗。还研究了37例接受保守治疗的良性前列腺增生(BPH)患者的生活质量。关于总体健康感觉,接受TAP治疗的前列腺癌患者主观感觉比接受DES治疗的患者更好。接受TAP治疗的患者或BPH患者的社交生活比接受DES治疗的患者受影响更小。接受TAP和DES治疗的前列腺癌患者的性生活质量比BPH患者更差。

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