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认知能力作为日本社区非残疾老年人功能衰退的预测指标:一项基于人群的4年前瞻性队列研究。

Cognitive performance as a predictor of functional decline among the non-disabled elderly dwelling in a Japanese community: a 4-year population-based prospective cohort study.

作者信息

Iwasa Hajime, Gondo Yasuyuki, Yoshida Yuko, Kwon Jinhee, Inagaki Hiroki, Kawaai Chieko, Masui Yukie, Kim Hunkyung, Yoshida Hideyo, Suzuki Takao

机构信息

Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho Itabashi-ku, Tokyo 173-0015, Japan.

出版信息

Arch Gerontol Geriatr. 2008 Jul-Aug;47(1):139-49. doi: 10.1016/j.archger.2007.07.008. Epub 2007 Sep 12.

Abstract

This study longitudinally examined the relationships between the specific domains of cognitive performance and functional decline among the community elderly. The study population was 119 men and 194 women aged 70-84 at baseline, who were examined at both baseline and in a 4-year follow-up survey. Katz's Index and the Tokyo Metropolitan Institute of Gerontology Index of Competence (TMIG-IC) were used for measuring the functional capacities of basic activities of daily living (BADL) and higher-level competence, respectively. For the purpose of analyses, declines in each subscale of functional capacity during the follow-up period were used as outcome variables; and specific domains of cognitive performances, including information processing speed, executive function, orientation, and episodic memory at baseline, were used as independent variables. Multiple logistic regression analyses, adjusted for the potential confounders, showed that information processing speed and orientation were associated independently and inversely with BADL decline, and that information processing speed and executive function were related independently and inversely to higher-level competence decline. These results suggested that information processing speed and orientation are reliable predictors for decline in BADL, and information processing speed and executive function are also reliable predictors for decline in higher-level competence among the community elderly.

摘要

本研究纵向考察了社区老年人认知表现的特定领域与功能衰退之间的关系。研究对象为119名男性和194名女性,基线年龄在70 - 84岁之间,在基线期和4年随访调查中均接受了检查。分别使用Katz指数和东京都老年医学研究所能力指数(TMIG - IC)来测量日常生活基本活动(BADL)的功能能力和高级能力。为了进行分析,将随访期间功能能力各子量表的衰退作为结果变量;将基线时认知表现的特定领域,包括信息处理速度、执行功能、定向和情景记忆,作为自变量。经潜在混杂因素调整的多重逻辑回归分析表明,信息处理速度和定向与BADL衰退独立且呈负相关,信息处理速度和执行功能与高级能力衰退独立且呈负相关。这些结果表明,信息处理速度和定向是BADL衰退的可靠预测指标,信息处理速度和执行功能也是社区老年人高级能力衰退的可靠预测指标。

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