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一种微妙的平衡:肾移植、免疫抑制与坚持医疗方案的协商

A delicate balance: negotiating renal transplantation, immunosuppression and adherence to medical regimen.

作者信息

Cook Peta S, McCarthy Alexandra

机构信息

Queensland University of Technology, Australia.

出版信息

Health (London). 2007 Oct;11(4):497-512. doi: 10.1177/1363459307080875.

Abstract

Despite the volume of biomedical and psychosocial discourse surrounding both renal transplantation and the immune system, there is a limit to current understandings of immunosuppression in the context of kidney transplantation. For example, we do not know how the immunosuppressed renal transplant recipient experiences and understands their immune system and body. In addition, we do not know if the patient is as fixated on ;graft survival' as their healthcare team or whether other concerns are more relevant. What is missing is the discourse of those who actually 'live' the medically altered immune system in the context of renal transplantation. We propose that this gap in knowledge is bound to an acknowledged problem among renal transplant recipients and their healthcare teams--a lack of compliance with recommended medical regimens. Our argument here is that an exploration of patient intimacy with transplant-related immunosuppression might illuminate a different understanding of this experience that could enhance health professionals' understanding and their subsequent approach to treatment. We contend that the embodied and contextual experience of the patient needs to be equally valued in order to enhance patient outcomes.

摘要

尽管围绕肾移植和免疫系统的生物医学及心理社会论述颇多,但目前对肾移植背景下免疫抑制的理解仍存在局限。例如,我们并不清楚免疫抑制的肾移植受者如何体验和理解自身的免疫系统及身体。此外,我们也不知道患者是否像其医疗团队那样执着于“移植肾存活”,或者其他问题是否更为重要。所缺失的是那些在肾移植背景下实际“生活”于医学改变后的免疫系统中的人的论述。我们认为,这一知识空白与肾移植受者及其医疗团队中一个公认的问题相关——对推荐医疗方案的依从性不足。我们在此的观点是,探索患者与移植相关免疫抑制的亲密关系,可能会揭示对这种体验的不同理解,从而增进医护人员的理解及其后续的治疗方法。我们主张,为了改善患者的治疗效果,患者的具体情境体验需要得到同等重视。

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