Zand Martin S
Nephrology Unit, Kidney and Pancreas Transplant Programs, University of Rochester Medical Center, Rochester, New York 14642, USA.
Semin Dial. 2005 Nov-Dec;18(6):511-9. doi: 10.1111/j.1525-139X.2005.00098.x.
Monitoring of immunosuppression therapy in renal transplant recipients is essential for good patient and graft survival. Monitoring includes frequent laboratory assays of serum immunosuppression levels, patient visits to assess and treat side effects, and vigilance for medication interactions. We review the various immunosuppression medications commonly used in renal transplantation, including usual dosing and side effects. Monitoring assays are discussed, as well as the frequency of monitoring and patient visits. Finally, we discuss several common clinical scenarios that often require adjustment of immunosuppression medications or regimens.
监测肾移植受者的免疫抑制治疗对于患者和移植物的良好存活至关重要。监测包括频繁进行血清免疫抑制水平的实验室检测、患者就诊以评估和治疗副作用,以及警惕药物相互作用。我们回顾了肾移植中常用的各种免疫抑制药物,包括常用剂量和副作用。讨论了监测检测方法,以及监测频率和患者就诊情况。最后,我们讨论了几种通常需要调整免疫抑制药物或方案的常见临床情况。