Falcão L M, Abreu P, Adragão P, Ventosa A, Canada M, Bonhorst D, Gomes R S
Serviço de Cardiologia, Hospital de Santa Cruz.
Rev Port Cardiol. 1991 Nov;10(11):817-22.
Evaluation of a WPW Syndrome population by non invasive methods; identification of the sudden death risk; results of treatment and patient selection for Electrophysiologic Studies (EPS).
Retrospective study.
Arrhythmology Outpatients Clinic from a Cardiac Department.
Successive patients older than 12 years with a WPW pattern on the ECG and history of paroxysmal tachycardia followed-up for a period of 46 +/- 29 months.
The clinical, ECG, Holter, stress test and echocardiographic data from 32 patients, were analysed. A study evaluating clinical follow up and the results of treatment was done.
The group of patients was very symptomatic. The main complaint was a feeling of tachycardia (84.4%). Orthodromic tachycardia was documented in 7 cases and atrial fibrillation with rapid ventricular rate in five. Intermittent delta wave pattern was found in 21 patients, with 11 cases identified by Holter and 4 by stress test. A predominant left accessory pathway was found (47%), but the anteroseptal location was frequent too (25%). The echocardiogram was not useful in any case. Eighty per cent of the patients became asymptomatic with medical treatment. Beta blockers and amiodarone (the last chance) were the most useful drugs. No mortality was found in the study group. EPS was considered for the 5 patients with paroxysmal atrial fibrillation and the 7 cases resistant to medical treatment.
The difficulty to define the risk of a population with WPW Syndrome by non invasive methods was demonstrated. Eighteen one cases were included in a low risk group, due to the intermittent WPW pattern in the ECG. A high risk group was considered for the 5 patients with atrial fibrillation with fast ventricular rate. The risk was not established in 9 cases. Most of the patients became asymptomatic by medical treatment.
采用非侵入性方法评估预激综合征(WPW)人群;识别猝死风险;治疗结果及电生理检查(EPS)的患者选择。
回顾性研究。
心脏科心律失常门诊。
连续入选年龄大于12岁、心电图有WPW图形且有阵发性心动过速病史的患者,随访46±29个月。
分析32例患者的临床、心电图、动态心电图、负荷试验及超声心动图数据。进行了一项评估临床随访及治疗结果的研究。
该组患者症状明显。主要主诉为心动过速感(84.4%)。记录到7例顺向型心动过速和5例房颤伴快速心室率。21例患者发现间歇性δ波图形,其中11例由动态心电图检出,4例由负荷试验检出。发现左旁路占优势(47%),但前间隔部位也较常见(25%)。超声心动图在所有病例中均无帮助。80%的患者经药物治疗后无症状。β受体阻滞剂和胺碘酮(最后手段)是最有效的药物。研究组未发现死亡病例。5例阵发性房颤患者和7例药物治疗无效的患者接受了电生理检查。
证实了采用非侵入性方法难以界定WPW综合征人群的风险。18例患者因心电图间歇性WPW图形被纳入低风险组。5例房颤伴快速心室率患者被视为高风险组。9例患者的风险未确定。大多数患者经药物治疗后无症状。