Pavie A, Mesnildrey P, Gandjbakhch I, Cabrol C, Fontaine G, Franck R, Grosgogeat Y, Slama R
Arch Mal Coeur Vaiss. 1984 Jun;77(6):606-15.
Surgical atrioventricular disconnection is a possible means of treating patients with severe paroxysmal arrhythmias resistant to medical treatment due to the Wolff-Parkinson-White syndrome. Between 1971 and April 1982 we operated 50 patients (38 men and 12 women) with the WPW syndrome. Thirty seven patients were operated for arrhythmias (paroxysmal tachycardia) resistant to medical therapy or with a high risk of sudden death. Thirteen patients had associated cardiac disease with less severe arrhythmias (aortic valve disease: 6 cases; mitral and aortic valve disease: 3 cases; mitral valve disease: 3 cases, and atrial septal defect: 1 case). The causes of paroxysmal tachycardia were atrial fibrillation (13 cases), atrial flutter (2 cases), orthodromic reciprocating tachycardia (30 cases), with associated atrial fibrillation in 9 cases, and with associated atrial flutter in 4 cases. Antidromic reciprocating tachycardia was present in 2 cases. In 3 cases, the preexcitation was a chance finding. Electrophysiological studies performed before and after antiarrhythmic drug administration showed type A WPW (LV preexcitation) in 23 cases, and type B WPW (RV preexcitation) in 20 cases. The ECG was normal in the horizontal plane in 7 cases. The atrioventricular accessory pathway was permeable in both directions in 39 cases; in 9 cases the pathway was permeable only in the retrograde direction and in 2 cases it was permeable only in the anterograde direction. In 7 patients an atrio-hisian short circuit was demonstrated. The site of the accessory conduction pathway was located by epicardial mapping, the first surgical stage, in the left lateral region of the atrioventricular junction (28 cases), in the right lateral region (6 cases), in the posterior septal region (15 cases) (right sided in 4 cases, left sided in 11 cases), and in the anterior septal region (1 case). The accessory pathway (so-called Bundle of Kent) was interrupted by atrioventricular disconnection. Six patients died during surgery, mainly at the beginning of the series; the operative risk is now low (1 death in the last 34 cases: 2,95%). Complete interruption of the accessory pathway was obtained in 38 cases, 1 of which had to be reoperated. Three patients had an incomplete result due to partial interruption or the presence of a second accessory pathway. However, these patients no longer have severe arrhythmias. Surgical section failed in 3 cases, but the patients are now controlled by medical therapy.(ABSTRACT TRUNCATED AT 400 WORDS)
外科房室分离术是治疗因预激综合征导致严重阵发性心律失常且药物治疗无效的患者的一种可行方法。1971年至1982年4月期间,我们对50例(38例男性和12例女性)预激综合征患者进行了手术。37例患者因药物治疗无效的心律失常(阵发性心动过速)或有猝死高风险而接受手术。13例患者伴有心脏病且心律失常较轻(主动脉瓣疾病:6例;二尖瓣和主动脉瓣疾病:3例;二尖瓣疾病:3例;房间隔缺损:1例)。阵发性心动过速的病因包括心房颤动(13例)、心房扑动(2例)、顺向性折返性心动过速(30例),其中9例伴有心房颤动,4例伴有心房扑动。2例存在逆向性折返性心动过速。3例患者的预激是偶然发现。在抗心律失常药物给药前后进行的电生理研究显示,23例为A型预激综合征(左心室预激),20例为B型预激综合征(右心室预激)。7例患者水平面心电图正常。39例患者的房室旁路在两个方向均有传导性;9例患者的旁路仅在逆向有传导性,2例仅在顺向有传导性。7例患者证实存在房希氏短路。通过心外膜标测确定了附加传导通路的位置,在第一阶段手术中,位于房室交界左侧区域(28例)、右侧区域(6例)、后间隔区域(15例)(右侧4例,左侧11例)和前间隔区域(1例)。通过房室分离术中断了附加通路(所谓的肯特束)。6例患者在手术期间死亡,主要在该系列手术初期;目前手术风险较低(最近34例中有1例死亡:2.95%)。38例患者实现了附加通路的完全中断,其中1例不得不再次手术。3例患者由于部分中断或存在第二条附加通路而结果不完全。然而,这些患者不再有严重心律失常。3例手术切断失败,但这些患者目前通过药物治疗得到控制。(摘要截取自400字)