Hollister L E, Boutros N
Harris Country Psychiatric Center, Department of Psychiatry, University of Texas Medical School, Houston.
J Psychiatry Neurosci. 1991 Nov;16(4):194-8.
During a three-year period, 337 CT or MR scans were ordered for psychiatric patients in a teaching hospital. Scans were normal in 185 instances, equivocal in 34, and abnormal in 118 instances. When a history of neurologic disorder and/or the presence of abnormal neurologic/organic mental signs was positive, scans were abnormal in 74% of cases; when these indicators were negative, scans were normal in 72% of cases. In all, only 4 new diagnoses were made. Two patients, both with markedly abnormal neurological findings, were shown to have brain tumors, which changed their management. Two others showed abnormalities which would have been missed, both of which were of no clinical consequence. The following are suggested as sound indications for ordering CT or MR brain imaging among psychiatric patients: 1) positive history of head injury, stroke or other neurologic disease, as well as suspected Alzheimer disease or multi-infarct dementia; 2) presence of abnormal neurologic signs or organic mental signs, such as confusion or cognitive decline; and, 3) a first psychotic break or personality change after the age of 50 years.
在三年时间里,一家教学医院为精神科患者安排了337次CT或MR扫描。扫描结果正常的有185例,不明确的有34例,异常的有118例。当存在神经系统疾病史和/或异常的神经系统/器质性精神体征呈阳性时,74%的病例扫描结果异常;当这些指标为阴性时,72%的病例扫描结果正常。总共只做出了4项新诊断。两名患者,均有明显异常的神经系统检查结果,被诊断出患有脑肿瘤,这改变了他们的治疗方案。另外两名患者显示出本会被漏诊的异常情况,但均无临床意义。以下被建议作为为精神科患者安排脑部CT或MR成像的合理指征:1)头部受伤、中风或其他神经系统疾病的阳性病史,以及疑似阿尔茨海默病或多发梗死性痴呆;2)存在异常的神经系统体征或器质性精神体征,如意识模糊或认知能力下降;以及3)50岁后首次出现精神病发作或人格改变。