Moles J K, Franchina J J, Sforza P P
Department of Psychiatric Medicine, University of Virginia, Salem, USA.
Gen Hosp Psychiatry. 1998 Sep;20(5):282-91. doi: 10.1016/s0163-8343(98)00040-1.
Computerized tomography (CT) continues to be extensively utilized to exclude intracranial pathology in psychiatric practice, but little is known about clinical risk factors, which might predict those patients most likely to benefit from the procedure. We reviewed 150 cases of psychiatric patients who received CT scans to exclude intracranial pathology. We assessed the relationships of patient age, psychiatric diagnosis, and findings from neurologic and cognitive examinations to CT results that influenced patient care, and overall normal and abnormal CT results. Fifty-three percent of the CT scans were abnormal, 11% influenced patient care, and only 2% identified potentially reversible lesions. Cognitive exam results and, to a lesser extent, neurologic exam results, were sensitive predictors of CT findings that influenced patient care. All patients with clinically influential CT results had cognitive deficits and all but one had neurologic deficits. Patients older than 60 years of age and those with organic mental syndromes were most likely to have clinically influential CT findings. Our results suggest that utilizing specific clinical risk factors such as findings from clinical examinations, patient age, and psychiatric diagnosis, to guide the ordering of CT scans, can greatly increase the yield of the procedure for psychiatric patients, without excess medical morbidity.
计算机断层扫描(CT)在精神科实践中仍被广泛用于排除颅内病变,但对于哪些临床风险因素可能预测出最有可能从该检查中获益的患者,我们却知之甚少。我们回顾了150例接受CT扫描以排除颅内病变的精神科患者。我们评估了患者年龄、精神科诊断以及神经学和认知检查结果与影响患者治疗的CT结果之间的关系,以及CT结果总体正常和异常的情况。53%的CT扫描结果异常,11%影响了患者治疗,仅有2%发现了潜在可逆性病变。认知检查结果以及在较小程度上神经学检查结果,是影响患者治疗的CT检查结果的敏感预测指标。所有CT结果对临床有影响的患者均有认知缺陷,除一人外均有神经学缺陷。年龄大于60岁的患者以及患有器质性精神综合征的患者最有可能出现对临床有影响的CT检查结果。我们的结果表明,利用特定的临床风险因素,如临床检查结果、患者年龄和精神科诊断,来指导CT扫描的开具,可以显著提高该检查对精神科患者的收益,而不会增加过多的医疗发病率。